A study of in vitro antibacterial activity of lanthanides complexes with a tetradentate Schiff base ligand.

Objective: To establish the antibacterial activity of lanthanides complexes with a tetradentate Schiff base ligand L.

Methods: (N, N'-bis (1-naphthaldimine)-o-phenylenediamine) was prepared from the condensation of 2-hydroxy-1-naphthaldehyde with o-phenylenediamine in a molar ratio of 2:1. The antimicrobial activity of the resultant Ln (III) complexes was investigated using agar well diffusion and micro-broth dilution techniques; the latter was used to establish the minimum inhibitory concentrations for each compound investigated.