Publications by authors named "Mu-Wen Wang"
Objective: To improve the accuracy of prostate cancer (PCa) detection by focusing biopsy on the suspected lesion manifested by MRI with the total number of biopsy cores relatively unchanged.
Methods: A prospective randomized analysis was performed on 262 cases of suspected PCa detected by multi-parametric MRI (mp-MRI), each with a single suspected lesion with 10 μg/L≤ PSA <20 μg/L. All the patients underwent targeted transrectal prostate biopsy guided by fusion imaging of MRI with transrectal ultrasonography (TRUS), using the 6X+6 strategy (6 cores in the suspected region and another 6 in the systematic prostate) for 134 cases and the traditional 12+2X method (12 cores in the systematic prostate and 2 in the suspected region) for the other 128.
Article Synopsis
- The study investigates the role of PlncRNA-1 in inducing apoptosis in prostate cancer cells by examining its relationship with the Her-2 pathway in both cancer and normal prostate tissues.
- In prostate cancer tissues, high expression levels of PlncRNA-1 and Her-2 were correlated, while silencing PlncRNA-1 in LNCaP cells led to decreased Her-2 and cyclinD1 levels, indicating a regulatory effect.
- Flow cytometry results demonstrated altered cell cycle phases in both LNCaP and RWPE-1 cell lines depending on the expression of PlncRNA-1, suggesting its influence on cell proliferation and apoptosis via the Her-2 pathway.
Objective: To investigate the efficacy and safety of tamsulosin, an α(1A)-adrenoceptor antagonist, as a potential male contraceptive.
Methods: Forty healthy male volunteers were equally divided into 2 groups, each of which received placebo and tamsulosin sequentially in a crossover manner. Ejaculatory profile was examined 4 to 6 hours after administration and adverse effects were noted.
[Transperitoneal laparoscopic enucleation of renal angiomyolipoma: a report of 10 cases].
Zhonghua Wai Ke Za Zhi
September 2005
Objective: To evaluate the feasibility and clinical effect of transperitoneal laparoscopic enucleation of renal angiomyolipoma (RAML) without obstruction of renal pedicle.
Methods: Ten patients with renal angioleiomyoma (tumor diameter < 4 cm) were operated by transperitoneal laparoscopy without obstruction of renal pedicle. The operating time, blood loss, hospital stay after operation, intraoperative and postoperative complications and the operative effect were observed.
Chronic pelvic pain syndrome(CPPS) which is also named by chronic nonbacterial prostatitis is a common urologic disease. This disease could not be treated effectively and affects the living quality of the patients. This article reviews the progress on the CPPS about its definition, classification, etiology (e.
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