Publications by authors named "Mu-Gen Dai"

Background: Postoperative complications are vital factors affecting the prognosis of patients with hepatocellular carcinoma (HCC), especially for complex hepatectomy. The present study aimed to compare perioperative complications between laparoscopic and robotic complex hepatectomy (LCH vs. RCH).

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Background & Aims: To examine the association of the history of preoperative antiviral therapy (AVT) with the tumor recurrence and overall survival in HBV-related HCC patients undergoing curative-intent hepatectomy.

Methods: Patients who underwent curative-intent hepatectomy for HBV-related HCC between 2014 and 2019 at 4 Chinese hospitals were analyzed. Patients were categorized as having undergone preoperative antiviral therapy (AVT) > 1 year or without antiviral therapy (non-AVT).

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Article Synopsis
  • The study investigates the impact of a three-dimensional (3D) printed dry-laboratory model on planning laparoscopic liver resection (LLR) for patients with complex hepatobiliary diseases.
  • Patients using the 3D model experienced significantly fewer complications, including lower rates of intraoperative blood loss and bile leakage, compared to those who relied on traditional imaging.
  • The findings suggest that 3D models are beneficial in reducing postoperative complications and can serve as a protective factor in surgical planning.
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Background And Aims: The prognosis of patients with hepatocellular carcinoma (HCC) undergoing hepatectomy is unsatisfactory, especially for those with microvascular invasion (MVI). This study aimed to determine the impact of adjuvant transcatheter arterial chemoembolization (TACE) and Lenvatinib on the prognosis of patients with HCC and MVI after hepatectomy.

Methods: Patients diagnosed with HCC and MVI were reviewed, and stratified into four groups according to adjuvant TACE and/or Lenvatinib.

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Background: Platelet distribution width (PDW), but not platelet count, was found to more comprehensively reflect platelet activity. The present study, thus, aimed to evaluate the prognostic value of PDW to lymphocyte ratio (PDWLR) in patients with hepatocellular carcinoma (HCC) following hepatectomy.

Methods: Patients following hepatectomy were analyzed retrospectively.

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Background And Aims: Preoperative prediction of microvascular invasion (MVI) using a noninvasive method remain unresolved, especially in HBV-related in intrahepatic cholangiocarcinoma (ICC). This study aimed to build and validate a preoperative prediction model for MVI in HBV-related ICC.

Methods: Patients with HBV-associated ICC undergoing curative surgical resection were identified.

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Background: The long-term prognosis of patients with hepatocellular carcinoma (HCC) after surgery remains far from satisfactory, especially in patients with microvascular invasion (MVI). This study aimed to evaluate the potential survival benefit from adjuvant lenvatinib for patients with HCC and MVI.

Methods: Patients with HCC after curative hepatectomy were reviewed.

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Background: A foreign body in the digestive tract is a common disease in the clinic. However, it is rare for a foreign body to migrate into the liver. Most patients are diagnosed before or after perforation of the digestive tract.

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Article Synopsis
  • Acute pancreatitis is a rare complication of gastrointestinal endoscopy, especially in patients without common risk factors like alcoholism or gallstones.!
  • A 56-year-old woman experienced severe abdominal pain immediately after an upper endoscopy and was diagnosed with acute pancreatitis, leading to a specific treatment regimen.!
  • The case emphasizes the need to consider pancreatitis as a potential diagnosis when patients report abdominal pain after undergoing gastrointestinal procedures.
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Background: The nonspecific clinical, radiological and pathological characteristics of gastric can establish it as an imitator of other gastric diseases. The absence of primary or secondary lubricating lesions should not prevent consideration of gastric .

Case Summary: A 63-year-old female patient presented to the hospital with dull pain in the middle and upper abdomen without apparent cause for one week, which was aggravated for two days.

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Background: Gastroesophageal varices are a rare complication of essential thrombocythemia (ET). ET is a chronic myeloproliferative neoplasm (MPN) characterized by an increased number of blood platelets.

Case Summary: A 46-year-old woman, who denied a history of liver disease, was admitted to our hospital on presentation of hematemesis.

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Liver steatosis is characterized by lipid dysregulation and fat accumulation in the liver and can lead to oxidative stress in liver. Since proanthocyanidins are present in plant-based foods and have powerful antioxidant properties, we investigated whether proanthocyanidins can prevent oxidative stress and subsequent liver injury. Carbon tetrachloride (CCl4) treatment can cause steatosis in rats that models both alcoholic and non-alcoholic fatty liver disease in humans.

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