Fine mapping and identification of the downy mildew resistance gene BoDMR2 in Cabbage (Brassica oleracea L. var. capitata).

Background: Cabbage (Brassica oleracea L. var. capitata) is an important crop within the Brassica oleracea species and is extensively cultivated worldwide.

Optimization Method of Floating Fixture Layout for Distortion Control of Low-Stiffness Thin-Walled Beams.

The aim is to reduce the elastic deformation of the web and side walls of low-stiffness thin-walled beams when the floating fixture method is used. This paper takes the number and position of fixture points as the optimization variables, establishes a calculation model of elastic deformation, and constructs the objective function of maximum total elastic deformation. An optimized solution utilizing the augmented multiplier method is employed, which forms the basis for the fixture layout optimization method to reduce the elastic deformation of low-stiffness thin-walled beams.

Neuroprotective Effects of Metformin on Cerebral Ischemia-Reperfusion Injury: Modulation of JNK and p38 MAP Kinase Signaling Pathways.

Cerebral ischemia-reperfusion injury (CIRI) is a significant pathological process in stroke, characterized by neuronal cell death and neurological dysfunction. Metformin, commonly used for diabetes management, has been noted for its neuroprotective properties, though its effects on CIRI and the mechanisms involved remain unclear. This study explored the neuroprotective impact of metformin on CIRI, focusing on its potential to modulate the c-Jun N-terminal kinase (JNK) and p38 MAP kinase (p38) signaling pathways.

Chloroplast C-to-U editing, regulated by a PPR protein BoYgl-2, is important for chlorophyll biosynthesis in cabbage.

Leaf color is an important agronomic trait in cabbage ( L. var. ), but the detailed mechanism underlying leaf color formation remains unclear.

Plant non-coding RNAs: The new frontier for the regulation of plant development and adaptation to stress.

Most plant transcriptomes constitute functional non-coding RNAs (ncRNAs) that lack the ability to encode proteins. In recent years, more research has demonstrated that ncRNAs play important regulatory roles in almost all plant biological processes by modulating gene expression. Thus, it is important to study the biogenesis and function of ncRNAs, particularly in plant growth and development and stress tolerance.

Large-scale gene expression alterations introduced by structural variation drive morphotype diversification in Brassica oleracea.

Brassica oleracea, globally cultivated for its vegetable crops, consists of very diverse morphotypes, characterized by specialized enlarged organs as harvested products. This makes B. oleracea an ideal model for studying rapid evolution and domestication.

Transcriptome Analysis Reveals Key Genes and Pathways Associated with the Regulation of Flowering Time in Cabbage ( L. var. ).

Flowering time is an important agronomic trait in cabbage ( L. var. ), but the molecular regulatory mechanism underlying flowering time regulation in cabbage remains unclear.

A Whole-Genome Assembly for , A Pathogen Causing Downy Mildew in Cabbage ( var. L.).

is a global pathogen that can cause leaf necrosis and seedling death, severely threatening the quality and yield of cabbage. However, the genome sequence and infection mechanisms of are still unclear. Here, we present the first whole-genome sequence of isolate BJ2020, which causes downy mildew in cabbage.

Introgression of clubroot resistant gene into L. from based on homoeologous exchange.

Clubroot is a soil-borne disease in cabbage ( L. var. L.

Comparative Transcriptome Analysis Reveals a Potential Regulatory Network for Ogura Cytoplasmic Male Sterility in Cabbage ( L.).

Ogura cytoplasmic male sterility (CMS) lines are widely used breeding materials in cruciferous crops and play important roles in heterosis utilization; however, the sterility mechanism remains unclear. To investigate the microspore development process and gene expression changes after the introduction of and , cytological observation and transcriptome analysis were performed using a maintainer line, an Ogura CMS line, and a restorer line. Semithin sections of microspores at different developmental stages showed that the degradation of tapetal cells began at the tetrad stage in the Ogura CMS line, while it occurred at the bicellular microspore stage to the tricellular microspore stage in the maintainer and restorer lines.

Glucosinolate Biosynthetic Genes of Cabbage: Genome-Wide Identification, Evolution, and Expression Analysis.

Cabbage ( var. ) is a vegetable rich in glucosinolates (GSLs) that have proven health benefits. To gain insights into the synthesis of GSLs in cabbage, we systematically analyzed GSLs biosynthetic genes (GBGs) in the entire cabbage genome.

protects against ischemic stroke by targeting .

Background: Ischemic stroke is a brain dysfunction disease caused by vascular obstruction. The expression of many kinds of microRNAs (miRNAs) is related to ischemic stroke. MiRNA has the ability to reduce or save ischemic injury.

Exercise Regulates the Lactate Receptor HCAR1 and ERK1/2-PI3K/Akt Pathways to Promote Cerebral Angiogenesis.

Background: We aimed to explore the ole and mechanism of lactate receptor (HCAR1) in the angiogenesis of leptomeningeal fibroblast-like cells.

Methods: Human brain fibroblast-like cells were selected and some cells were deactivated, analyzed and compared with HCAR1 mRNA and protein expressions in deactivated/normal cells. HCAR1 mice and wild type (WT) mice were selected and divided into WT, WT exercise, HCAE1 KO and HCAE1 KO exercise groups, with 10 mice for each group.

Resource Screening and Inheritance Analysis of sp. Race 2 Resistance in Cabbage ( var. ).

Cabbage ( var. ) Fusarium wilt (CFW) is a disease that poses a critical threat to global cabbage production. Screening for resistant resources in order to support the breeding of resistant cultivars is the most reliable approach to control this disease.

BoGDB: An integrative genomic database for L.

is an important species due to its high economic and nutritional value. Moreover, it is an ideal model for studies of morphology and genome evolution. In the genomic era, with massive "omics" data being generated, a high-efficiency platform is crucial to deepen our understanding of this important species.

Research on Clamping Action Control Technology for Floating Fixtures.

By adaptively releasing deformation during machining, floating clamping significantly raises the machining quality of aircraft structural parts. The fundamental issue to be resolved is how to precisely control the clamping action of the floating fixtures. In this study, the machining process of aircraft beams was studied, utilizing the finite element method (FEM) from the perspective of strain energy evolution.

Mechanism and Utilization of Ogura Cytoplasmic Male Sterility in Cruciferae Crops.

Hybrid production using lines with cytoplasmic male sterility (CMS) has become an important way to utilize heterosis in vegetables. Ogura CMS, with the advantages of complete pollen abortion, ease of transfer and a progeny sterility rate reaching 100%, is widely used in cruciferous crop breeding. The mapping, cloning, mechanism and application of Ogura CMS and fertility restorer genes in , , and other cruciferous crops are reviewed herein, and the existing problems and future research directions in the application of Ogura CMS are discussed.

Transcriptome Analysis Reveals Key Genes and Pathways Associated with the Petal Color Formation in Cabbage ( L. var. ).

Petal color is an important agronomic trait in cabbage ( L. var. ).

An Identification System Targeting the SRK Gene for Selecting S-Haplotypes and Self-Compatible Lines in Cabbage.

Cabbage ( L. var. ) self-incompatibility is important for heterosis.

PSMC2 is overexpressed in glioma and promotes proliferation and anti-apoptosis of glioma cells.

Background: This study aims to investigate the effect of PSMC2 expression on the clinical prognosis of glioma patients and its molecular mechanism.

Methods: TCGA multi-tumor screening and survival analysis were combined to explore the differential expression of PSMC2 in multi-tumor. PSMC2 expression in glioma and normal tissues was detected by Western blot and RT-qPCR.

Plant SWEET Family of Sugar Transporters: Structure, Evolution and Biological Functions.

The SWEET (sugars will eventually be exported transporter) family was identified as a new class of sugar transporters that function as bidirectional uniporters/facilitators and facilitate the diffusion of sugars across cell membranes along a concentration gradient. SWEETs are found widely in plants and play central roles in many biochemical processes, including the phloem loading of sugar for long-distance transport, pollen nutrition, nectar secretion, seed filling, fruit development, plant-pathogen interactions and responses to abiotic stress. This review focuses on advances of the plant SWEETs, including details about their discovery, characteristics of protein structure, evolution and physiological functions.

Butylphthalide Inhibits TLR4/NF-B Pathway by Upregulation of miR-21 to Have the Neuroprotective Effect.

Stroke is a disease with the highest incidence rate and the highest mortality rate in the world. The study aims to verify the neuroprotective effect of Butylphthalide. The mice were divided into sham group, MCAO group, and MCAO + Butylphthalide-treated group.

Organelle Comparative Genome Analysis Reveals Novel Alloplasmic Male Sterility with in L.

Ogura CMS is an alloplasmic male-sterile line introduced from radish by interspecific hybridization and protoplast fusion. The introduction of alien cytoplasm resulted in many undesirable traits, which affected the yield of hybrids. Therefore, it is necessary to identify the composition and reduce the content of alien cytoplasm in Ogura CMS.

Carotenoid Biosynthetic Genes in Cabbage: Genome-Wide Identification, Evolution, and Expression Analysis.

Carotenoids are natural functional pigments produced by plants and microorganisms and play essential roles in human health. Cabbage ( L. var.

Genetic Diversity and Population Structure of the Xanthomonas campestris pv. campestris Strains Affecting Cabbages in China Revealed by MLST and Rep-PCR Based Genotyping.

Xanthomonas campestris pv. campestris (Xcc) is the causal agent of black rot for cruciferous vegetables worldwide, especially for the cole crops such as cabbage and cauliflower. Due to the lack of resistant cabbage cultivars, black rot has brought about considerable yield losses in recent years in China.