Background: Globally, 10% of pregnant women and 13% of postpartum women experience mental disorders. In Bangladesh, nearly 50% of mothers face common mental disorders, but mental health services and trained professionals to serve their needs are scarce. To address this, the government of Bangladesh's Non-Communicable Disease Control program initiated "Wellbeing Centers," telemental health services in selected public hospitals.
View Article and Find Full Text PDFThe issue of global climate change is increasingly worrisome, particularly for countries heavily reliant on agriculture. To reduce the negative impact of climate change on agriculture, farmers of Bangladesh started adopting different climate smart agriculture (CSA) practices. The CSA sustainably increases productivity, resilience, and food security, which can contribute to the achievement of a number of sustainable development goals (SDGs).
View Article and Find Full Text PDFCholera rapid diagnostic tests (RDTs) are vulnerable to virulent bacteriophage predation. We hypothesized that an enhanced cholera RDT that detects the common virulent bacteriophage ICP1 might serve as a proxy for pathogen detection. We previously developed a monoclonal antibody (mAb) to the ICP1 major capsid protein.
View Article and Find Full Text PDFBackground: The recent human monkeypox (mpox) outbreak in 2022 has become a serious concern due to its rapid expansion to various non-endemic countries. There is limited information about the knowledge regarding mpox among the Bangladeshi population. Therefore, this study's objectives were to: (i) determine the level of knowledge regarding mpox among undergraduate and post-graduate students in Bangladesh, and (ii) assess the determinants of knowledge regarding mpox among the study sample.
View Article and Find Full Text PDFMymensingh Med J
January 2025
The pandemic Covid-19 not only caused great public health problems but also caused enormous distress, especially for medical staff. The cross-sectional study aimed to investigate the prevalence rate of insomnia and to confirm the social factors among medical support staff in hospitals during the Covid-19 pandemic from 1st July 2020 to December 31st 2020. This study was conducted at Dhaka Medical College and Hospital (DMCH), Kurmitola General Hospital (KGH), Kuwait Bangladesh Friendship Government Hospital and Mugda Medical College and Hospital located at Dhaka and Tungipara UHC from Tungipara, Gopalganj, Bangladesh.
View Article and Find Full Text PDFMultiple myeloma (MM) is a haematological neoplasm of mature B-cell lineage origin. It is characterized by abnormal clonal proliferation of plasma cells and presence of monoclonal protein in serum and / or urine. This study was conducted to observe the International Staging System (ISS) status and trends of relapse.
View Article and Find Full Text PDFThis article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal).
View Article and Find Full Text PDFBackground: Age plays a significant role in susceptibility to enterotoxigenic (ETEC) infections, yet the distribution of ETEC virulence factors across age groups remains understudied. This study investigated the differential pathogenic profiles ETEC across various age groups, emphasizing the importance of selecting potential ETEC antigens tailored to infection patterns in infants and adults in Bangladesh.
Methods: This study utilized the icddr,b's 2% systematic hospital surveillance data of diarrheal patients ( = 14,515) from 2017 to 2022 to examine the age-specific pathogenesis and clinical manifestations of ETEC infections.
Global efforts have been made to address environmental and health concerns by promoting and adopting renewable natural resources. This study investigated the role of bagasse-based wood vinegar to synthesize and stabilize silver nanoparticles. We present a simple bottom-up approach to produce silver nanoparticles using the green reducing agent.
View Article and Find Full Text PDFThis research presents an explicit analysis of the effects of sintering temperature (T) on the structural, morphological, magnetic, and optical properties of CuMgFeO nanoferrites synthesized via the sol-gel method. To accomplish it, Cu-Mg ferrite NPs were sintered at temperatures ranging from 300 to 800 °C in increments of 100 with a constant holding duration of 5 h. Thermogravimetric analysis was used to observe the degradation of organic components and the thermally stable zone of the material.
View Article and Find Full Text PDFThe assembly of biological systems forms nonequilibrium patterns with different functionalities through molecular-level communication via stepwise sequential interaction and activation. The mimicking of this molecular signaling offers extensive opportunities to design self-assemblies of bioinspired synthetic nonequilibrium systems to develop molecular robots with active, adaptive, and autonomous behavior. Herein, the design and construction of biomolecular motor system, microtubule (MT)-kinesin based molecular swarm system, are reported through stepwise sequential interactions of DNA.
View Article and Find Full Text PDFChem Biodivers
December 2024
Cryptococcus neoformans causes cryptococcal meningitis, which is lethal to immune-compromised people, especially AIDS patients. This study employed diverse in silico techniques to find the best phytochemical to block farnesyltransferase (FTase). Based on molecular docking, the top two compounds selected from a screening of 5807 phytochemical compounds from 29 medicinal plants were CID_8299 (hydroxyacetone) and CID_71346280 (1,7-bis (4-hydroxyphenyl)-1,4,6-heptatrien-3-one), with docking scores of -5.
View Article and Find Full Text PDFThe heme enzymes of the cytochrome P450 superfamily (CYPs) catalyse the selective hydroxylation of unactivated C-H bonds in organic molecules. There is great interest in applying these enzymes as biocatalysts with a focus on self-sufficient CYP 'fusion' enzymes, comprising a single polypeptide chain with the electron transfer components joined to the heme domain. Here we elucidate the function of the self-sufficient CYP116B46 fusion enzyme, from the thermophilic bacterium Tepidiphilus thermophilus.
View Article and Find Full Text PDFGrape pomace (GP) is a byproduct of the viticulture industry and shows promise for feeding dairy cattle as well as reducing enteric methane (CH) emissions. This study investigates the potential of using fresh GP in dairy cow feeding and its effects on CH emissions. Multiparous Holstein dairy cows (n = 24, 205 ± 39 DIM) were housed in free stall barns and provided rations consisting of alfalfa hay, wheat hay, almond hulls, cottonseed, and grain mix.
View Article and Find Full Text PDFThe recent outbreak of lumpy skin disease virus (LSDV) in the wetland areas of Bangladesh presents a significant concern for both animal health and regional biosecurity. Epidemiological investigations into nine major outbreaks in the wetland areas revealed distinctive clinical symptoms in affected cattle, including elevated body temperature, excessive salivation, and the presence of skin nodules. Histopathological examination unveiled larger nodules compared to previous outbreaks, along with signs of secondary infection.
View Article and Find Full Text PDFCOVID-19 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) had an adverse effect globally because it caused a global pandemic with several million deaths. This virus possesses spike protein that is cleaved or activated by Furin-like protease enzymes occurring by mammalian lung or respiratory cells to enter the mammalian body. The addition of the Furin cleavage site in SARS-CoV-2 makes it a more infectious and emerging virus than its ancestor's viruses.
View Article and Find Full Text PDFBackground: There is a shortage of rapid, accurate, and low-cost assays for diagnosing enteric fever. The dual-path platform for typhoid (DPPT) assay had high accuracy in retrospective studies with banked plasma samples. We aimed to evaluate the diagnostic accuracy of the DPPT assay in a prospective study using fingerstick capillary blood.
View Article and Find Full Text PDFJDR Clin Trans Res
December 2024
Aim: Pressing oral health care challenges pose prioritization dilemmas for governments. This study aimed to identify key determinants of prioritization in oral health policy in Denmark, Germany, the Netherlands, and the United Kingdom, as part of a series of the DELIVER project.
Methods: A literature review based on a search of PubMed and Google Scholar articles related to these countries from January 1, 2000, to October 17, 2023, and key informant interviews with policy makers were conducted to identify key trends in oral health policy choices and determinants of priority setting and resource allocation processes.
Background: University is a critical period regarding unhealthy changes in eating behaviors in students. University students often face significant changes in their eating habits and physical activity levels, which can impact their overall health.
Aims: To investigate the eating habits and sedentary behavior of university students in Dhaka.
Curr Opin Biotechnol
December 2024
Plants have evolved sophisticated molecular switches to perceive and respond to both endogenous and exogenous signals, enabling changes in form and function in response to environmental and developmental cues. As autotrophic, multicellular organisms, plants represent promising platforms for designing and engineering sense-and-report modules. Advances in protein engineering and functional screening have facilitated the reprogramming of native switches into biosensors capable of detecting novel small molecules.
View Article and Find Full Text PDFBackground: The convergence of healthcare and artificial intelligence (AI) introduces a transformative era in medical practice. However, the knowledge and attitudes of healthcare workers concerning the adoption of artificial intelligence in healthcare are currently unknown.
Aims: The primary objective was to investigate the knowledge and attitudes of healthcare professionals in Dhaka city, Bangladesh, regarding the adoption of AI in healthcare.
This article employs a Panel Mean Group Autoregressive Distributed Lag (PMG-ARDL) approach to investigate the interaction between carbon dioxide (CO2) emissions, Gross Domestic Product (GDP), fossil fuel, renewable energy consumption, trade, and their collective impact on life expectancy within the BRICS nations. The research reveals compelling findings. Notably, CO2 emissions and trade openness exhibit negative and statistically significant impact on life expectancy.
View Article and Find Full Text PDFThe worldwide prevalence of thyroid disease is on the rise, representing a chronic condition that significantly impacts global mortality rates. Machine learning (ML) approaches have demonstrated potential superiority in mitigating the occurrence of this disease by facilitating early detection and treatment. However, there is a growing demand among stakeholders and patients for reliable and credible explanations of the generated predictions in sensitive medical domains.
View Article and Find Full Text PDFThe broiler industry is crucial for rural economies, but it faces challenges in enhancing animal performance and well-being, particularly due to heat stress and ammonia (NH) in grow-out houses. This study investigates the effectiveness of air velocity (AV) treatment in reducing heat stress and NH emissions while also improving litter conditions to enhance animal welfare. Conducted at the North Carolina State University's poultry engineering laboratory, the research used six identical controlled chambers, exposing broilers to High and Low AV treatments from 28 to 61 days across four flocks during the summers of 2017 and 2018.
View Article and Find Full Text PDF