Dual function of angiogenin-4 inducing intestinal stem cells and apoptosis.

The intestinal epithelium is the first line of host defense, and its homeostasis is dependent on soluble factors that comprise the crypt niche. Antimicrobial proteins are one of the mediators to maintain gut homeostasis. Angiogenin-4 (Ang4) is a member of the ribonuclease A superfamily and plays a pivotal role in antimicrobial activity against gut microbiota.

Human and mouse angiogenins: Emerging insights and potential opportunities.

Angiogenin, a well-known angiogenic factor, is crucial to the angiogenesis in gastrointestinal tumors. Human angiogenin has only one gene, whereas the murine angiogenin family has extended to incorporate six genes. Evolutionary studies have suggested functional variations among murine angiogenin paralogs, even though the three-dimensional structures of angiogenin proteins are remarkably similar.

Implications of COVID-19 on oxbow lake Fisher's community, Bangladesh: resilience to food security against probable natural calamities.

The purpose of studying the consequence of COVID-19 on oxbow lake () fisher's community is to counteract the negative impacts on livelihoods with food security and figure out diversified resilience options for sustaining basic needs of life. Individual questionnaire interviews, oral history, focus group discussion, and telephonic interviews were among the methodological techniques used to gather primary data. The fisher's community was impaired with income, food and feeding habit, health and marketing.

Identification of Crucial Amino Acid Residues for Antimicrobial Activity of Angiogenin 4 and Its Modulation of Gut Microbiota in Mice.

Angiogenin 4 bearing ribonuclease activity is an endogenous antimicrobial protein expressed in small and large intestine. However, the crucial amino acid residues responsible for the antibacterial activity of Ang4 and its impact on gut microbiota remain unknown. Here, we report the contribution of critical amino acid residues in the functional regions of Ang4 to its activity against LT2 and the effect of Ang4 on gut microbiota in mice.

Life-history traits of ten commercially important small indigenous fish species (SIFS) in the Oxbow lake (Southwestern Bangladesh): key for sound management.

For the first time, we revealed the life-history traits including growth pattern (length-weight relationships, LWRs), condition factors, form factor (a), first sexual maturity (L), age at first sexual maturity (t), life span (t), natural mortality (M), asymptotic length (L), and optimum catchable length (L) of ten commercially important small indigenous fish species (SIFS) in the Oxbow lake (Baor), southwestern regions of Bangladesh. A total of 1651 specimens were sampled during January to December 2020 with traditional fishing gears including seine nets, gill nets, and lift nets. Individual total length (TL) and body weight (BW) were measured by digital slide calipers and digital balance, respectively.