Publications by authors named "Mrutyunjaya Mishra"
Article Synopsis
- This study investigates how the brain compensates for congenital deafness by focusing on tactile discrimination abilities through high-resolution fMRI imaging.
- The research involved 35 congenitally deaf individuals and 35 hearing controls, who performed tasks to identify objects by touch while their brain activity was analyzed using advanced statistical techniques.
- Results showed that deaf participants had unique neural activations in areas usually tied to hearing, and they excelled in reaction times compared to hearing individuals, suggesting adaptive changes in their brain that enhance tactile processing.
Article Synopsis
- Conducted a study using fMRI to analyze brain responses during sign language, picture, and word processing tasks in 35 deaf participants versus 35 hearing participants.
- Deaf individuals showed significant brain activation in specific regions during sign language and picture processing, revealing adaptations in their neural pathways due to auditory deprivation.
- The study highlighted unique activation patterns and connectivity in the deaf population, suggesting compensatory mechanisms in their language processing compared to hearing counterparts.
Within the intricate matrices of cognitive neuroscience, auditory deprivation acts as a catalyst, propelling a cascade of neuroanatomical adjustments that have, until now, been suboptimally articulated in extant literature. Addressing this gap, our study harnesses high-resolution 3 T MRI modalities to unveil the multifaceted cortical transformations that emerge in tandem with congenital auditory deficits. We conducted a rigorous cortical surface analysis on a cohort of 90 congenitally deaf individuals, systematically compared with 90 normoacoustic controls.
View Article and Find Full Text PDFBackground And Purpose: Early hearing loss causes several changes in the brain structure and function at multiple levels; these changes can be observed through neuroimaging. These changes are directly associated with sensory loss (hearing) and the acquisition of alternative communication strategies. Such plasticity changes in the brain might establish a different connectivity pattern with resting-state networks (RSNs) and other brain regions.
View Article and Find Full Text PDFA loss of hearing in early life leads to diversifications of important white matter networks. Previous studies related to WM alterations in adult deaf individuals mainly involved univariate analysis of fractional anisotropy (FA) data and volumetric analysis, which yielded inconsistent results. To address this issue, we investigated the FA value alterations in 38 prelingual adult deaf individuals and compared the results with those obtained from the same number of adults with normal hearing by using univariate (tract-based spatial statistics) and multivariate (source-based morphometry) methods.
View Article and Find Full Text PDFSensory input for hearing plays a significant role in the development of human brain. Absence of an early auditory input leads to the alteration of important neural regions, which in turn results in a complex process known as cross-modal neuroplasticity. Previous studies related to the structural brain alteration of adult deaf individuals have shown inconsistent results.
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