Publications by authors named "Mrinmoy Gautam"
Article Synopsis
- The study focuses on creating chitosan nanoparticles (CS-NPs) loaded with gemcitabine and capped with folic acid and silver nanoparticles, aimed at improving cancer treatment through targeted drug delivery.
- Characterization techniques such as dynamic light scattering and transmission electron microscopy confirmed the size and properties of the nanoparticles, which were influenced by their compositions and conditions.
- In vitro testing showed that the CS-NPs effectively released the drug in lower pH environments and had higher cytotoxicity on human breast cancer cells compared to neutral pH levels, indicating potential for site-specific cancer therapy.
The objective of the study is to elucidate the effect of bark hydroalcoholic extract (AMHE) and the role of its constituents marmelosin, umbelliferone, and Para-coumaric acid in attenuating neuropathic pain. Peripheral neuropathy was induced by vincristine 100 μg/ml. AMHE was administered in three dose levels (100, 200 and 300 mg/kg) for 21 days.
View Article and Find Full Text PDFThe study comprises exploring the effects of saponins from Tribulus terrestris (TT) in attenuating the neuropathic pain caused by vincristine (100 μg/ml i.p.) for 10 days (in two 5 day cycles with 2 days pause).
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