Publications by authors named "Mridul Umesh"

Microplastic contamination of terrestrial and aquatic environment has gained immense research attention due to their potential ecotoxicity and biomagnification property when enterer into food chain. Heterogenous nature of microplastics coupled with their ability to combine with other emerging pollutants have increased the severity of this crisis. Existing detection methods often fails to accurately quantify the amount of microplastic components present in environmental and biological samples.

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The cost-effective production of commercially important biopolymers, such as chitosan, has gained momentum in recent decades owing to its versatile material properties. The seasonal variability in the availability of crustacean waste and fish waste, routinely used for chitosan extraction, has triggered a focus on fungal chitosan as a sustainable alternative. This study demonstrates a cost-effective strategy for cultivating an endophytic fungus isolated from Pichavaram mangrove soil in a pineapple peel-based medium for harvesting fungal biomass.

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Endocrine disrupting chemicals or carcinogens have been known for decades for their endocrine signal disruption. Endocrine disrupting chemicals are a serious concern and they have been included in the top priority toxicants and persistent organic pollutants. Therefore, researchers have been working for a long time to understand their mechanisms of interaction in different human organs.

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Lignocellulosic waste generation and their improper disposal has accelerated the problems associated with increased greenhouse gas emissions and associated environmental pollution. Constructive ways to manage and mitigate the pollution associated with lignocellulosic waste has propelled the research on biochar production using lignocellulose-based substrates. The sustainability of various biochar production technologies in employing lignocellulosic biomass as feedstock for biochar production not only aids in the lignocellulosic biomass valorization but also helps in carbon neutralization and carbon utilization.

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Polyethylene Terephthalate (PET) is a polymer which is considered as one of the major contaminants to the environment. The PET waste materials can be recycled to produce value-added products. PET can be converted to nanoparticles, nanofibers, nanocomposites, and nano coatings.

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Diverse practices implementing biopolymer-producing bacteria have been examined in various domains lately. PHAs are among the major biopolymers whose relevance of PHA-producing bacteria in the field of crop improvement is one of the radical unexplored aspects in the field of agriculture. Prolonging shelf life is one serious issue hindering the establishment of biofertilizers.

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Driven by the imperative need for sustainable and biodegradable materials, this study focuses on two pivotal aspects: cellulose extraction and dye removal. The alarming repercussions of non-biodegradable food packaging materials on health and the environment necessitate the exploration of viable alternatives. Herein, we embark on creating easily degradable biopolymer substitutes, achieved through innovative crafting of a biodegradable cellulose sheet sourced from extracted cellulose.

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The current study demonstrates the potential of Cassia fistula seed carbon (CFSC), a waste lignocellulosic biomass, to eliminate Cd (II) ion-from saturated liquid samples. The efficient removal of about 93.2% (w/v) of Cd (II) ions from 10 mg/L concentration was achieved within 80 min of treatment.

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Endocrine disrupting compounds are the chemicals which mimics the natural endocrine hormones and bind to the receptors made for the hormones. Upon binding they activate the cascade of reaction which leads to permanent activating of the signalling cycle and ultimately leads to uncontrolled growth. Pesticides are one of the endocrine disrupting chemicals which cause cancer, congenital birth defects, and reproductive defects in non-target organisms.

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AMPs are small oligopeptides acting as integral elements of the innate immune system and are of tremendous potential in the medical field owing to their antimicrobial and immunomodulatory activities. They offer a multitude of immunomodulatory properties such as immune cell differentiation, inflammatory responses, cytokine production, and chemoattraction. Aberrancy in neutrophil or epithelial cell-producing AMPs leads to inflammation culminating in various autoimmune responses.

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The present study explores natural pigments as sustainable alternatives to synthetic textile dyes. Due to their therapeutic applications and easy production, fungal pigments have gained attention. However, data on pigment production using solid-state fermentation and optimization is limited.

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The exponential increase in the use and careless discard of synthetic plastics has created an alarming concern over the environmental health due to the detrimental effects of petroleum based synthetic polymeric compounds. Piling up of these plastic commodities on various ecological niches and entry of their fragmented parts into soil and water has clearly affected the quality of these ecosystems in the past few decades. Among the many constructive strategies developed to tackle this global issue, use of biopolymers like polyhydroxyalkanoates as sustainable alternatives for synthetic plastics has gained momentum.

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The inevitable need for waste valorisation and management has revolutionized the way in which the waste is visualised as a potential biorefinery for various product development rather than offensive trash. Biowaste has emerged as a potential feedstock to produce several value-added products. Bioenergy generation is one of the potential applications originating from the valorisation of biowaste.

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The present study describes the isolation and characterization of Bacillus tropicus LS27 capable of keratinolytic protease production from Russell Market, Shivajinagar, Bangalore, Karnataka, with its diverse application. The ability of this strain to hydrolyze chicken feathers and skim milk was used to assess its keratinolytic and proteolytic properties. The strain identification was done using biochemical and molecular characterization using the 16S rRNA sequencing method.

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Massive accumulation of unprocessed banana peels enthralls sustainable issues as they are eventually dumped as landfills leading to emission of obnoxious gasses. To avoid these persisting challenges the present study shims lights on chitosan production from the characterised fungal strain using banana peel hydrolysate as an effective medium. Substantial amount of carbohydrate in banana peels serves as a potential solution for fungal chitosan production in a view to attain a circular bioeconomy and repurposed for synthesis of beneficial products in a cost effective manner.

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Microplastics are the small fragments of the plastic molecules which find their applications in various routine products such as beauty products. Later, it was realized that it has several toxic effects on marine and terrestrial organisms. This review is an approach in understanding the microplastics, their origin, dispersal in the aquatic system, their biodegradation and factors affecting biodegradation.

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Immensely expanding world population and narrowing arable land for agriculture is a mighty concern faced by the planet at present. One of the major reasons for decline in arable lands is the increased soil salinity, making it unfavourable for crop cultivation. Utilisation of these saline land for agriculture is possible with suitable invention for improving the soil quality.

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Modernization and industrialization has undoubtedly revolutionized the food and agro-industrial sector leading to the drastic increase in their productivity and marketing thereby accelerating the amount of agro-industrial food waste generated. In the past few decades the potential of these agro-industrial food waste to serve as bio refineries for the extraction of commercially viable products like organic acids, biochemical and biofuels was largely discussed and explored over the conventional method of disposing in landfills. The sustainable development of such strategies largely depends on understanding the techno economic challenges and planning for future strategies to overcome these hurdles.

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The present research work reports the biosynthesis of hydroxyapatite (HAp) from eggshells and green synthesis of HAp from eggshells with incorporation of Piper betel leaf extract (PBL-HAp) using microwave conversion method. Although there are several works on synthesis of HAp from eggshells and other calcium and phosphorus rich substrates, the incorporation of herbal extract with HAp to promote antimicrobial and antibiofilm activity is less explored and reported. This research work highlights a simple and cost-effective method for development of antimicrobial biomaterials by combining the concepts of waste management, biomaterial science, and herbal medicine.

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