Publications by authors named "Mrazova J"

Background: is nowadays valued for its high content of biologically active substances, the main group of which are polyphenols, which include anthocyanins, flavonols, flavanols, proanthocyanidins and phenolic acids. From the available sources, we can conclude that extracts and juices from black chokeberry have a great potential in human nutrition and influence on their health.

Objective: The research was to evaluate the effect of regular consumption of 100% organic chokeberry juice on selected anthropometric and lipid parameters of overweight or obese women.

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Flaxseed is known for its numerous health benefits and is often used in the prevention and treatment of civilizational diseases. This study aimed to evaluate the impact of consuming crushed flaxseed on cardiovascular risk in 51 menopausal women. The intervention lasted for 8 weeks, during which participants received a daily dose of 40 g of crushed flaxseed from two varieties with differing lignan contents.

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Background: In recent years, a wider range of bakery products with a lower glycaemic response can be observed in the food industry. This contributes to the provision of a wider range of cereal bakery products. The gradual increase in the consumption of brown bread is significant, but despite this, white bread remains a part of the typical Western diet.

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Background: Sea buckthorn contains almost 200 nutrients and bioactive substances, including phenolic compounds such as flavonoids, vitamins, proteins, amino acids, minerals, alkaloids, chlorophyll derivatives, amines, organic acids, fatty acids and phytosterols. Human and animal studies suggest that sea buckthorn may have a variety of beneficial effects: cardioprotective, antiatherogenic, antioxidant, anticancer, immunomodulatory, antibacterial, antiviral and antiinflammatory.

Objective: The aim of this study was to evaluate the effect of regular consumption of 100% sea buckthorn juice on the risk factors of cardiovascular diseases in women of productive age with hypercholesterolemia.

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Acrylamide (AA) a widely used industrial chemical is also formed during food processing by the Maillard reaction, which makes its exposure to humans almost unavoidable. In this study, we used as a model organism to investigate AA toxicity (10 or 20 mM concentration) in eukaryotes. In , AA delays cell growth causes oxidative stress by enhancement of ROS production and triggers excitement of the antioxidant defence system resulting in the division arrest.

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Background: Cardiovascular diseases (CVD) due to their large expansion and high mortality represent a serious problem for society. Ischemic heart disease and myocardial infarction is the leading cause of death and morbidity in both men and women in Europe, although is lower in women than in men.

Objective: To evaluate the occurrence of cardiovascular risk factors and the impact of selected dietary habits on lipid profile and body mass index in adult men hospitalized after myocardial infarction in the Cardiocenter Nitra in 2010-2020.

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The epidemiologic studies from the recent years indicate that high consumption of foods rich in bioactive compounds has a positive effect on human health and could diminish the risk of numerous diseases, such as cancer, heart disease, stroke, Alzheimer's disease, diabetes, cataracts, and even diseases related to age. From all species of fruit, definitely consumption of berries due to its high content of bioactive constituents prevents the risk of cardiovascular disease, oxidative stress and diabetes. The primary phenolic compounds in berries are flavonoids, particularly the anthocyanins.

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The objective of the present study was to evaluate the effect of short-term consumption of bitter apricot seeds phytonutrients on cardiovascular risk factors with a special focus on LDL cholesterol subfractions using the Lipoprint system. A group of 34 adult volunteers (21 female/13 male) consumed 60 mg kg of body weight of bitter apricot seeds daily for 42 days. Subjects were divided into two groups: one with normal cholesterol levels (NTC) and one with elevated total cholesterol levels (ETC).

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Background: Overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. Obesity is associated with many chronic diseases, including cardiovascular disease and diabetes, and recently the role of overweight and obesity in lung disease has received new interest. Chronic obstructive lung disease is the third-leading cause of death globally, and both obesity and diet appear to play roles in its pathophysiology.

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The aim of the research was to evaluate the impact of consumption of pork enriched with selenium on selenium concentration, antioxidant status and lipid parameters of consumers. The research involved 59 probands in four experiments from the general population of Slovakia. The probands consumed 200 g of enriched meat with organic selenium from pork fed with selenized yeast three times a week during one month.

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Background: Cardiovascular disease (CVD) is the leading cause of death worldwide and largely preventable through improving diet quality and other lifestyle factors. In recent years, dietary recommendations have shifted towards diets high in plant-based foods and low in animal-based foods for the prevention of chronic diseases.

Objective: This study aims to evaluate the relationship between seeds consumption, lipid profile and body mass index (BMI) in a group of 889 (313 female and 576 male) randomly selected patients hospitalized in the Nitra Cardio Center, Slovakia.

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Natural products have been attracting increasing attention in human diet, both due to the possible negative effects of synthetic food additives on human health and the increased consumer perception. Apricot seeds contain a wide variety of bioactive components and their consumption is associated with a reduced risk of chronic diseases. The objective of the present study was to evaluate the effect of consumption of bitter apricot seeds on blood lipid and endocrine profile in Slovak women (n = 18, 41.

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This study evaluated the associations between selected dietary habits and lipid profiles in a group of 800 randomly selected patients hospitalized in the Nitra Cardio Center, Slovakia. Patients were aged 20-101 years (only men, the average age was 61.13 ± 10.

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The aim of the research was to evaluate the effect of consumption of selenium-enriched pork on selected health indicators of probands. The intake of feed mixture with increased organic selenium at the dose of 0.3 mg.

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Background: Bread is one of the world’s most consumed food commodity. However, in the last years consumption of bread and bakery products has declined, especially in the Western population. The reason for concern is the weight gain and presence of gluten in these products.

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Reported here is the first analytical methodology for the enantiomeric determination of chiral trace organic contaminants (TOrCs) in soil. Direct enantioselective separations were achieved on a Chirobiotic V2 column operated in polar ionic mode. Initial screening of vancomycin stationary phases found Chirobiotic V2 better suited for multi-residue separation of chiral TOrCs than Chirobiotic V due to differences in the ligand linkage chemistry.

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Background: Chronic obstructive pulmonary disease (COPD) is an airway inflammatory disease caused by inhalation of toxic particles, mainly cigarette smoking, and now is accepted as a disease associated with systemic characteristics.

Objective: The aim of this work was to investigate and compare selected biochemical parameters in patients with and without COPD.

Material And Methods: Observation group consisted of clinically stable patients with COPD (n = 60).

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Background: Cigarette smoking is a major public health problem, which leads to the formation of chronic obstructive pulmonary disease (COPD) and is one of the main causes of avoidable death and disability worldwide.

Objective: The aim of study was analysis and comparison of the visceral fat in the body of the three groups of subjects (non-smokers, smokers and COPD patients) by Tanita Viscan 140.

Material And Methods: The control group was composed of: (1) non-smokers (n=30), consisted of 13 males (43.

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Background: γ-Aminobutyric acid (GABA) is a potentially bioactive component of foods and pharmaceuticals. The aim of this study was screen lactic acid bacteria belonging to the Czech Collection of Microorganisms, and microorganisms (yeast and bacteria) from 10 different food sources for GABA production by fermentation in broth or plant and animal products.

Results: Under an aerobic atmosphere, very low selectivity of GABA production (from 0.

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Injection of botulinum toxin (BT) and pneumatic dilatation are available methods in nonsurgical treatment of achalasia. Authors anticipate beneficial effect of prior BT injection on the success of pneumatic dilatation and duration of its effect. There are no long-term data available to assess efficacy of combined treatment.

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The authors used between October 1993 and January 1997 in 131 patients with inoperable malignant or benign stenosis of the oesophagus an expansible metal stent. In 25 patients the stenosis was in the upper third of the oesophagus, in 44 in the medium part, in 53 in the lower third of the oesophagus and in 9 patients in the area of the anastomosis. All patients suffered at the time when the stent was introduced from marked dysphagia (stage 3-4 according to the international classification).

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The authors describe three patients with episodes of abdominal pain where despite a negative finding in the urine sonography revealed dilatation of the hollow system. Urography proved stenosis of the pyeloureteral junction. The authors discuss the cause of abdominal pain.

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The effect of repeated administration of allopurinol (50 mg.kg-1 48, 24, and 4 hours before analysis) on the activity of enzymes of degradation and resynthesis of adenine nucleotides was studied. The activity of xanthine dehydrogenase and xanthine oxidase was inhibited in the heart, liver and kidney and the activity of membrane-bound 5'-nucleotidase was particularly elevated in the heart and brain, suggesting that membrane transport processes may be affected.

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Using 24-hour Holter ECG examinations, the authors assessed ECG changes in a group of 86 healthy students of a Bratislava secondary school. The students were 14-18 years old. Their mean age was 15.

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