Prognostic scores in primary biliary cholangitis.

Evaluating prognostic scores' utility in predicting ursodeoxycholic acid (UDCA) biochemical response (BR) and long-term liver-related complications in primary biliary cholangitis (PBC) patients. This retrospective single-center study included 50 predominantly female PBC patients (median age: 56) on UDCA treatment. BR was defined by Paris II criteria.

Development of a Web Application based on Machine Learning for screening esophageal varices in cirrhosis.

Introduction: Esophageal varices (EV) are a common manifestation of portal hypertension in cirrhotic patients. Upper gastrointestinal endoscopy (UGE) is the gold standard for diagnosing EV. However, it is an invasive examination with a relatively high cost.

East-central Tunisian patients with colorectal adenocarcinoma: a comparative study of the clinicopathological features between patients under 50 years of age and older patients.

Introduction: Colorectal cancer is a major public health problem. In younger patients, its incidence continues to rise and its prognosis appears to be worse. Its treatment is based on curative surgery associated with neo-adjuvant and adjuvant therapies.

Primary Hepatic Lymphoma in a Patient with Chronic Hepatitis B.

Primary hepatic lymphoma is a rare disease, accounting for only 0.1% of malignant liver tumors. The subtype of diffuse large B-cell lymphoma (DLBCL) is more infrequent.

Isolated pancreatic tuberculosis mimicking pancreatic cancer in an immunocompetent host: An elusive diagnosis.

Isolated pancreatic tuberculosis is a very rare condition, even in areas of the world where the disease is highly prevalent. We report the case of isolated pancreatic tuberculosis in 54-year-old immunocompetent women, presenting as a solid mass of the pancreatic head with multiple lymphadenopathy mimicking a pancreatic carcinoma. The diagnosis was made with endoscopic ultra sound with fine needle aspiration and the treatment with anti-tuberculosis agents allowed the disappearance of the pancreatic mass and the regional lymphadenopathy.

Gastric diverticula as a diagnostic and therapeutic challenge: Case report and review of literature.

Introduction: Gastric diverticula are a rare condition characterized by a pouch protruding from the gastric wall. It is commonly asymptomatic and managed without surgery. Gastric diverticulotomy is indicated in the case of symptomatic or complicated diverticula.

Cirrhotic cardiomyopathy.

The presence of cardiocirculatory dysfunction in liver cirrhosis has been described since 1960 and it was exclusively attributed to alcoholic cardiomyopathie. Only in the last two decades, the term of cirrhotic cardiomyopathy (CCM) was introduced to describe cardiac dysfunction in patients with cirrhosis. This entity is currently underdiagnosed because the disease is usually latent and manifests when the patient is under stress.

Paneth cell adenocarcinoma of the colon: A rare entity.

Introduction: Amongst the morphotypes of colorectal adenocarcinomas, the rich cell type of Paneth constitutes a rare histopathologic variant of adenocarcinoma, which can be observed all along the digestive tract but also in other organs such as the prostate or the breast. About 24 cases were found in the literature, with only 7 cases within the colon and appendix.

Presentation Of Case: We report the case of a 50-year-old man, without past medical history, complaining of abdominal pain and constipation for 3 months.

Duodenal duplication: a rare cause of abdominal pain in adults.

Duodenal duplication is an extremely rare congenital abnormality that occurs mostly in children. It represents only 2% to 12% of all gastrointestinal tract duplication. Its clinical presentation is highly variable and non-specific making the positive diagnosis very difficult.

Candida albicans: a cause or a consequence of esophageal intramural pseudo-diverticulosis.

Esophageal intramural pseudo-diverticulosis is a rare disease of unknown etiology. It is characterized by multiple pseudodiverticula with segmental or diffuse involvement of the esophagus. We report, the case of a 78-year-old male who suffered from severe dysphagia.

Anemia revealing a collagenous gastritis in a young Tunisian man.

Collagenous gastritis is a rare entity, characterized by the deposition of a subepithelial collagenous band with an inflammatory infiltrate in the mucosa. We report the first Tunisian case revealed by severe anemia. Lesions were limited to the stomach and remained unchanged on 3 series biopsies during a 24 month follow up despite treatment with corticosteroids.

Squamous cell carcinoma of the rectum cured after chemoradiation.

The primary squamous cell carcinoma of the rectum is a rare tumor that presents epidemiological, etiopathogenic and evolutionary characteristics different from those of adenocarcinoma . We report the case of a primary squamous cell  carcinoma well  differentiated  from medium-high   rectal junction in a 59 year old patient treated with a chemoradiation first ,followed by surgical resection. However, the anatomical examination of the  surgical specimen did not show tumoral tissue.

Colonic intussusception caused by a sigmoidal lipoma: A case report.

Introduction: Intussusception is a relatively common condition seen in children. In comparison, adult intussusception is rare and is often secondary to inflammatory diseases, benign or malignant tumors and motility disorders. Being a benign cause, lipomas appear as a particularly rare gastrointestinal tumor.

Quality of life in inflammatory bowel disease in Tunisian patients.

Background: The management of the health-related quality of life (HRQL) is increasingly considered as an important treatment goal in chronic diseases including inflammatory bowel diseases (IBD).

Aim: The aim of our study was to determine the impact of IBD on HRQLand identify the factors involved in the deterioration of HRQL in these patients.

Methods: We conducted a case-control study including 108 patients; 66 had Crohn's disease (CD) and 42 had ulcerative colitis (UC).

Gastrointestinal Biopsy in Henoch-Schönlein Purpura: A Great Diagnostic Contribution.

Unlabelled: Henoch-Schönlein purpura is an IgA-mediated immune vasculitis which is characterized by purpuric lesions and osteoarticular, intestinal and sometimes renal manifestations. The histopathological substrate of this entity is leucocytoclastic vasculitis (LCV) with IgA deposits seen on immunohistochemistry. We here report the case of a 27-year-old woman with abdominal pain and cutaneous purpura.