Evaluation of molecular apoptosis signaling pathways and its correlation with EBV viral load in SLE patients using systems biology approach.

Background: Considerable evidence supports that SLE could be related to apoptotic cells and EBV infection.

Objective: The aim of this study was to identify the transcriptional signature of EBV infection in SLE patients for survey of the molecular apoptosis signaling pathways.

Methods: The PBMCs gene expression profiles of healthy control and SLE patients were obtained from GEO.