Publications by authors named "Mozhdeh Nemati"
Article Synopsis
- Erythropoietin (EPO) is primarily used to treat anemia and also acts as a neuroprotective agent in the central nervous system by binding to its receptor, EPOR, on neurons and glial cells.
- The EPO-EPOR complex initiates specific signaling pathways in glial cells that may influence various neurological disorders, including Alzheimer's, Parkinson's, and conditions like stroke and trauma.
- The review emphasizes EPO's role across different glial cell types and suggests that understanding its non-blood-related actions could improve treatments for CNS disorders and highlight its neuroprotective capabilities.
Autism spectrum disorder (ASD) is a widespread neurodevelopmental disorder with unknown etiology. Dysfunction of several brain areas including the prefrontal cortex (PFC), hippocampus, and cerebellum is involved in cognitive and behavioral deficits associated with ASD. Several studies have reported a reduction in the number of parvalbumin-immunoreactive (PV) neurons in brain areas of ASD patients and animal models such as a shank mutant mouse model and rodents receiving fetal valproic acid (VPA) administration.
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