Publications by authors named "Mozhaev S"

The authors analyzed the results of 11C-methionine positron emission tomography (PET) in 101 patients with suspected recurrent brain tumor. The diagnosis was confirmed in 72 patients. The increased 11C-methionine uptake in the initial tumor area is considered to be a crucial PET evidence of a recurrent tumor.

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The study was based on the data of positron emission tomography (PET) and L-[methyl]-[11C]-methionine used in 117 patients with suspected brain tumor. PET data on 74 patients with histologically verified cerebral tumors were analyzed in detail. New additional criteria for assessing PET scans, which formed the PET syndromes of astrocytomas, anaplastic astrocytomas, and glioblastomas.

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A complex research of epileptogenic focus (electroencephalography, invasive electroencephalography, MRI, PET) has allowed to localize a primary epileptogenic zone in medial temporal epilepsy in amygdale in 52% of the patients, in the anterior hippocampus--in 30% cases, a simultaneous and equivalent involvement of both amygdale and anterior hippocampus was diagnosed in 18% of the patients examined. Stereotaxic selective amygdalehippocampotomy was found to be effective in patients with resistant medial and lateral temporal epilepsy. The attacks stopped in 36% of the cases.

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The paper summarizes experience with stereotactic operations by magnetic resonance imaging data by using a Russian OREOL stereotactic manipulator. It describes methods of preoperative preparation of patients by employing diagnostic magnetic resonance tomographs. A number of points of the procedure for identification and localization of deep target structures from magnetic resonance images in parkinsonism, temporal epilepsy and some mental disorders.

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PET data were compared with the results of computerized tomography (CT) and the neurological status of patients. The areas of decreased local cerebral blood flow (LCBF) and reduced local cerebral metabolic glucose rates exceeded those of brain injury shown by CT predominantly in patients with brain posttraumatic cysts. In a group of patients with posttraumatic atrophy documented by CT, PET demonstrated cortical and/or subcortical lesions in most cases, providing objective evidence for neurological symptoms.

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The local cerebral blood flow, oxygen tension, local impedance and intragastric pressure were examined in 13 patients with meningiomas of the middle third of the apical sagittal sinus at various stages of surgery including those after ablation of the intrasinus node and its reconstruction. In all the patients the decompressive cranial trepanation showed a blood stream enhancement but on the meningioma side. It is concluded that the degree of disturbances of oxygenative metabolism and blood circulation after the removal and reconstruction of the intrasinus node was dependent on the variant of the sinus injury.

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The authors analyze the results of surgical management of 242 patients with upper sagittal sinus meningiomas who have been treated in the past 20 years. All the patients were divided into 3 groups in accordance with the surgical policy and techniques of interventions and anesthesiological support. The type of sinus wall tumor lesion and its associated cerebral blood outflow disorders detected by electrophysiological studies in pre- and intraoperative periods determined surgical policy which along with microsurgical technique of recovery of the intact sinus and superficial veins of the brain enhanced the efficiency of operations up to 92.

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The paper deals with improvement of procedures for autografting a greater omental fragment to the vascular layer of the brain in its experimental ischemic lesions. The findings suggest that a functional vasculature has formed between the omentum and the meninx vasculosa just at hour 24 postautografting. This provides evidence to recommend the method for clinical application to compensate cerebral circulatory disorders in tumor-induced and vascular abnormalities in the brain.

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Under analysis are etiology, clinical picture and diagnosis of a septic thrombosis of cavernous sinuses in 28 patients. The authors have shown the interrelationship between local manifestations of the disease, injuries of the brain and its sheaths and septic complications (abscessing pneumonia as the most severe of them). A scheme of the complex treatment of patients with thrombosis of the cavernous sinus is proposed.

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