A computationally efficient approach for 2D-3D image registration.

2D-3D image registration has become an important tool in many clinical applications such as image-guided surgery and the kinematic analysis of bones in knee and ankle joints. A limitation of this approach is the need to recalculate the voxel values in the 3D volume for every iteration of the registration procedure. In this paper we propose a new 2D-3D image registration algorithm which uses the projected 2D data from the original 3D CT volume.