Identification of -Glcnacylated Proteins in .

Originally an anthropozoonosis in the Americas, Chagas disease has spread from its previous borders through migration. It is caused by the protozoan . Differences in disease severity have been attributed to a natural pleomorphism in .

Apart From Rhoptries, Identification of -GlcNAcylated Proteins Reinforces the Universality of the -GlcNAcome.

-linked β-N-acetylglucosaminylation or -GlcNAcylation is a widespread post-translational modification that belongs to the large and heterogeneous group of glycosylations. The functions managed by -GlcNAcylation are diverse and include regulation of transcription, replication, protein's fate, trafficking, and signaling. More and more evidences tend to show that deregulations in the homeostasis of -GlcNAcylation are involved in the etiology of metabolic diseases, cancers and neuropathologies.

Identification of O-GlcNAcylated proteins in Plasmodium falciparum.

Background: Post-translational modifications (PTMs) constitute a huge group of chemical modifications increasing the complexity of the proteomes of living beings. PTMs have been discussed as potential anti-malarial drug targets due to their involvement in many cell processes. O-GlcNAcylation is a widespread PTM found in different organisms including Plasmodium falciparum.