Background And Aims: Pharmacy students represent the future of healthcare professionals and with daily use of the internet for different activities has made internet addiction (IA) of a growing concern. The main objectives of this study were to 1) assess internet addiction among pharmacy undergraduate students as well as factors associated with it; 2) assess the relationships between internet addiction and common mental disorders (depression, anxiety, and stress), in addition to academic performance and body mass index factors.
Methods: We utilized a cross-sectional questionnaire that was conducted among 808 students of Egypt university pharmacy students across the country.
Introduction: To find genetic variants in the DRD4 and HTR2A genes' promoter regions and exons that are associated with tobacco smoking and nicotine addiction in Egyptian university students as well as to study the association between personality traits and smoking status.
Methods: A self-administered questionnaire about cigarette smoking and personality attributes (Big Five Inventory, ESPAD Questionnaire on Substance Abuse, and Buss-Perry Aggression Questionnaire). The participants in the study were 90 nonsmokers (NS) and 88 current smokers (CS), who were divided into two groups depending on their cigarette consumption per day (cpd): 55 heavy smokers (HS, >20 cpd) and 33 light smokers (LS, 1-10 cpd).
Mass vaccination is the most effective strategy against the spread of the COVID-19 pandemic. However, concerns about the vaccine's safety and effectiveness remain a huge obstacle to vaccine acceptance. The aim of the present study was to explore different COVID-19 vaccine outcomes, including the development of adverse events and/or COVID-19 infection following COVID-19 vaccination.
View Article and Find Full Text PDFBackground: A considerable amount of attention has been recently paid to the discovery of effective natural antidiabetic drugs. Terminalia chebula is considered as the mother of herbs, with reported antidiabetic activity. This study aims to evaluate the renal and hepatic protective profile of its antidiabetic therapeutic doses.
View Article and Find Full Text PDFPrevious studies have shown that caffeine attenuates stress-induced mood dysfunction and memory deterioration through neuronal adenosine A2A receptors antagonism. However, whether caffeine exerts this effect through modulating other molecular targets, which interfere with the resilience to social defeat stress in adolescent male mice is unknown. This study was conducted to investigate the role of caffeine in the behavioral responses to social stress induced by the sensory contact model (SCM) and the possible alteration of the gene expression level of Na/K ATPase pump.
View Article and Find Full Text PDFRecently, experimental studies demonstrated that 2-methoxyestradiol (2ME2) ameliorates high fat diet (HFD)-induced obesity and restores insulin sensitivity. However, the mechanisms underlying these effects are unveiled yet. The current study was undertaken to test the hypothesis that 2ME2 exerts its effects by modulating adipose tissue macrophages (ATMs) accumulation, polarization and immunophenotypes.
View Article and Find Full Text PDFThis study attempts to develop empirical correlations between average penetration resistance ([Formula: see text]), averaged velocities over depth up to bedrock depth ([Formula: see text]) and 30 m ([Formula: see text]) for shallow depth sites (having bedrock at a depth less than 25 m). A total of 63 shallow sites were assessed for penetration resistance values up to the bedrock from Standard Penetration Tests (SPT) and dynamic soil property analysis, i.e.
View Article and Find Full Text PDFGround-motion prediction equations that are used to predict acceleration values are generally developed for a 5% viscous damping ratio. Special structures and structures that use damping devices may have damping ratios other than the conventionally used ratio of 5%. Hence, for such structures, the intensity measures predicted by conventional ground-motion prediction equations need to be converted to a particular level of damping using a damping reduction factor (DRF).
View Article and Find Full Text PDFEndogenous ligands of Na/K-ATPase have been demonstrated to increase in kidney dysfunction and heart failure. It is also reported that Na/K-ATPase signaling function effects stem cell differentiation. This study evaluated whether Na/K-ATPase activation through its ligands and associated signaling functions affect bone marrow stromal cells (BMSCs, also known as bone marrow-derived mesenchymal stem cells) differentiation capacity.
View Article and Find Full Text PDFThe current study examined the role of Na/K-ATPase α1-subunit in animals subjected to 5/6th partial nephrectomy (PNx) using Na/K-ATPase α1-heterozygous (α1(+/-)) mice and their wild-type (WT) littermates. After PNx, both WT and α1(+/-) animals displayed diastolic dimension increases, increased blood pressure, and increased cardiac hypertrophy. However, in the α1(+/-) animals we detected significant increases in cardiac cell death in PNx animals.
View Article and Find Full Text PDFThe NR4A nuclear receptor NHR-6 is an essential regulator of spermatheca organogenesis in C. elegans. In this study, we perform a focused, RNAi-based screen to identify modifiers of partial nhr-6 loss of function.
View Article and Find Full Text PDFPediatric subtrochanteric femoral fractures are rare and have received limited attention in the literature Treatment is controversial. Different treatment options are used: skin traction, 90/90 skeletal traction, spica casting, cast bracing, internal fixation and external fixation. The aim of this study is to present our results with internal fixation of subtrochanteric femoral fractures in children using a reconstruction plate.
View Article and Find Full Text PDFBackground: The aim of this work was to study the association between blunted nighttime dipping of blood pressure (BP) and coronary artery stenosis in men.
Methods: Sixty-eight men (aged 52 +/- 11 years) with coronary artery disease (CAD) defined as >/=70% diameter stenosis, and a control group of 68 men, matched for age and risk factors without angiographic CAD were studied by ambulatory blood pressure monitoring. Patients were defined as nondippers when the nighttime systolic and diastolic BP decrease was <10%.
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