Thyroid hormones play essential roles in spermatogenesis, but their effects on infertile males remain poorly understood. This study aimed to evaluate the impact of combining carbimazole (CBZ) with vitamin E (VE) on testicular injury induced by experimental hyperthyroidism in adult albino rats, focusing on oxidative, inflammatory, and apoptotic pathways. In this experimental study, 64 adult male albino Wistar rats were divided into eight groups: Group I (control-untreated), Group II (CBZ-control), Group III (VE-control), Group IV (CBZ + VE-control), Group V (levothyroxine-induced testicular injury), Group VI (levothyroxine + CBZ-treated), Group VII (levothyroxine + VE-treated), and Group VIII (levothyroxine + CBZ + VE-treated).
View Article and Find Full Text PDFBackground: Many therapeutic modalities are available for treating genital warts; however, the effectiveness of both diphenylcyclopropenone and podophyllin is still controversial.
Aim: To evaluate the effectiveness and safety of diphenylcyclopropenone and podophyllin in treating genital warts.
Methods: This study included 57 patients, divided randomly into two groups.
Vitiligo has a major effect on sexual health because of the disfiguring skin lesions affecting self-image and self-esteem. However, this topic has not explored. This article aimed to assess the effect of vitiligo on genital self-image, sexual function, and quality of life in female patients.
View Article and Find Full Text PDFBackground: Acral vitiligo (AV) is resistant to treatment.
Aim: To evaluate efficacy and safety of combining carbon dioxide (CO2) laser and 5-fluorouracil (5FU) in treating AV.
Methods: This study included 68 adult patients with AV.
Introduction: Female genital mutilation/cutting (FGM/C) is a prevalent, deeply rooted traditional practice in Egypt.
Aims: Specification of the motives behind the continuation of FGM/C in Egyptian community and evaluation of the sexual function in women with FGM/C.
Methods: This cross-sectional study, involved 2,106 sexually active female participants with FGM/C.
Introduction: Psoriasis has a major impact on sexual health due to the disfiguring skin lesions affecting self-image and self-esteem. However, this topic has not been fully explored.
Aim: The study aims to assess sexual function in female patients with psoriasis.
Background: Our study evaluated the expression of vascular endothelial growth factor (VEGF), CD31 and D2-40 in involved and uninvolved skin of 18 patients with rosacea.
Methods: Immunostaining of facial skin specimens with VEGF, CD31 and D2-40 was compared between the lesional and the non-lesional skin of patients with erythemotelangiectatic and papulopustular rosacea.
Results: Significantly increased dermal expression of VEGF in lesional vs.