Human papillomavirus, gene mutation and estrogen and progesterone receptors in breast cancer: a cross-sectional study.

Introduction: recent studies show a good relationship between breast cancer (BC) and human papillomaviruses (HPV) wich is responsible for about 18% of BC cases. This study aimed to assess the relationship between different genotypes of HPV and the expression of P53 and retinoblastoma (RB) genes and estrogen and progesterone receptors in BC among Sudanese women.

Methods: one hundred and fifty tissue blocks were obtained from females diagnosed with BC.