Oral cannabidiol did not impair learning and memory in healthy adults.

Background: The effect of oral Cannabidiol (CBD) on interference during learning and memory (L&M) in healthy human volunteers has not been studied.

Method: A two-arm crossover, randomized, double-blind, placebo-controlled trial was conducted at Colorado State University Pueblo (CSU Pueblo) to evaluate the effects of 246 mg oral CBD on L&M in healthy adults. Among 57 healthy volunteers enrolled, 35 were included in the analyses.

Effects of Lead (Pb) from Smelter Operations in an Urban Terrestrial Food Chain at a Colorado Superfund Site.

Lead (Pb) is ubiquitous in urban environments, and it is a risk factor for wildlife. But wildlife are particularly at risk for exposure near smelters in urban areas where higher than safe Pb levels in the soil have the potential to transfer to the food chain. Therefore, we investigated whether wildlife are at risk of Pb exposure and differences in Pb bioaccumulation in trophic levels at a Superfund site in an urban area of Colorado.

Enhanced adsorptive removal of indigo carmine dye by bismuth oxide doped MgO based adsorbents from aqueous solution: equilibrium, kinetic and computational studies.

Novel doped MgO nanoadsorbents were effectively fabricated at various BiO doping concentrations (0, 2.5, 5 and 10%). DFT-D3 study showed that the doping is done by substitution of two magnesium atoms by two bismuth atoms with the creation of a vacancy of one Mg atom.

Smelting Remains a Public Health Risk Nearly a Century Later: A Case Study in Pueblo, Colorado, USA.

Pueblo, Colorado has a long history of smelting activities, and recent studies raised concerns about lead exposure. This study tested 240 children in Pueblo for blood lead levels (BLLs) and found a significant association between distance from old smelters and children BLLs. Around 7.

Arsenite exposure compromises early embryonic development in the Golden hamster.

The toxicity of arsenite to 8-cell stage hamster embryos was evaluated. Females were superovulated and mated; embryos were collected and grown for 72 h in culture medium containing vehicle control, 25, 50, 250, 500, or 750 nM arsenite. Morphological observations were taken at 0 and 24h increments.

Arsenic, cadmium, lead, and mercury in surface soils, Pueblo, Colorado: implications for population health risk.

Decades of intensive industrial and agricultural practices as well as rapid urbanization have left communities like Pueblo, Colorado facing potential health threats from pollution of its soils, air, water and food supply. To address such concerns about environmental contamination, we conducted an urban geochemical study of the city of Pueblo to offer insights into the potential chemical hazards in soil and inform priorities for future health studies and population interventions aimed at reducing exposures to inorganic substances. The current study characterizes the environmental landscape of Pueblo in terms of heavy metals, and relates this to population distributions.

Reproductive toxicity of the psoralens.

The psoralens are naturally occurring secondary metabolites in plants, including many fruits and vegetables. Health risks have been associated with handling or ingesting psoralen-containing plants, and with the use of synthetic psoralens in photochemotherapy of skin disorders. Our research has demonstrated that administration of the psoralens bergapten (5-methoxypsoralen) and xanthotoxin (8-methoxypsoralen) in the diet of female rats reduced birthrates, number of implantation sites, pups, corpora lutea, full and empty uterine weight, and circulating estrogen levels in a dose-dependent manner.