Publications by authors named "Moussa Ahmed"
Article Synopsis
- Emergency medicine residents faced challenges with receiving entrustable professional activity (EPA) assessments during their pediatric rotation due to untrained preceptors.
- A study was conducted involving faculty members to evaluate the effectiveness of a training workshop focused on supervising EPAs.
- Post-training results indicated an increase in EPA assessments for residents, suggesting that faculty development can enhance assessment opportunities in clinical rotations.
Sickle cell disease is one of the most common autosomal recessive genetic disorders with 23% and over 70% of men with this condition, experiencing episodes of ischaemic priapism and stuttering priapism, respectively, with potentially severe consequences. The effective prevention of sickle cell disease induced ischaemic priapism and stuttering priapism requires a multidisciplinary and multimodal approach. A search of the English literature was performed utilising Pubmed® and Google Scholar to identify publications on contemporary and novel treatment options, with their associated treatment outcomes if available, that are utilised to prevent stuttering priapism episodes and hence a fulminant ischaemic priapism.
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- Understanding reproductive success in domestic animals requires knowledge of sperm biology, fertilization, and conception processes.
- Key focus areas include sperm maturation, capacitation, the acrosome reaction, and gamete recognition for successful fertilization.
- Future research will advance reproductive techniques by examining molecular biology, immune interactions, environmental impacts, and multi-omics approaches to enhance fertility outcomes.
Article Synopsis
- - In this study, researchers created new compounds based on roflumilast to specifically inhibit the PDE-4B enzyme, using a set of synthesized compounds (4a-u, 5a-i, and 6) that were tested against PDE-4B and compared to roflumilast.
- - Four compounds (4i, 4k, 4p, and 4q) showed strong inhibitory activity with 4p being the most potent (IC = 5.50 nM), even outperforming roflumilast (IC = 2.36 nM) in terms of potency.
- - The selective inhibition characteristics of these compounds were analyzed, with compound 4k
Article Synopsis
- * A study of 41 children showed a 43.6% complete remission rate, with most achieving minimal residual disease (MRD) negativity.
- * Venetoclax was effective for bridging patients to transplant, with a 75% success rate, and those starting treatment with MRD <1% had significantly better outcomes in terms of MRD negativity and overall survival.
Article Synopsis
- The study aimed to create a new onco-functional outcome (OFO) classification for glioblastoma patients, combining the goals of complete tumor resection and avoiding functional loss into four categories.
- Analyzing data from 858 patients over ten years, they found that the OFO classification significantly influenced overall survival (OS) and progression-free survival (PFS) rates, especially in certain tumor types.
- The results showed that achieving the best outcome (OFO1) was linked to improved survival rates and higher likelihood of receiving additional therapy, particularly with awake craniotomy procedures being more effective in avoiding deficits.
Article Synopsis
- - The Learning-by-Concordance tool, designed by qualified educators, aims to enhance reasoning skills in uncertain contexts, but there's limited information on educators' experiences using it
- - This study investigates the beliefs and experiences of educators involved in the tool's design through qualitative research, gathering insights from four dialogue groups of 14 participants
- - Findings reveal that educators feel discomfort despite their expertise, highlighting themes of needing peer reassurance, feeling like impostors, and worries about the quality of instructional materials
Mitigating spill pollution in the Nile River is crucial to protecting aquatic life, water quality, and public health. Extensive studies focused on the assessment of water quality and hydrodynamics of the Nile River, but there have been relatively few studies that have applied integrated hydrodynamic and water quality modeling approaches to simulate actual accidents in the Nile Fourth Reach. The goal of this study is to develop advanced computational models to simulate accidental spills in the Nile River and track the resulting impacts on water quality.
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- Simulation is an effective training method for neonatal resuscitation, but COVID-19 limitations prompted the exploration of alternative training methods like 360-degree virtual reality (VR) videos.
- The study aimed to create a high-quality VR video of neonatal resuscitation simulations and assess its acceptability as a teaching tool.
- Results showed that participants had a positive reaction to the video, indicating it could enhance teaching in areas like crisis resource management and procedural skills, although cognitive load was higher than expected. Future research is necessary to evaluate the learning outcomes associated with the VR method.
Spatial distribution, geochemical processes of high-content fluoride and nitrate groundwater, and an associated probabilistic human health risk appraisal in the Republic of Djibouti.
Mohamed Osman Awaleh Tiziano Boschetti Moussa Mahdi Ahmed Omar Assowe Dabar Mohamed Abdillahi Robleh
Sci Total Environ
June 2024
Article Synopsis
- The Republic of Djibouti exclusively uses groundwater, facing health risks due to high fluoride (up to 14 mg/L) and nitrate (up to 256 mg/L) levels, necessitating a comprehensive analysis of 362 groundwater samples.
- Advanced geochemical tools and stable isotope ratios were applied to understand the mechanisms behind these enrichments, revealing that mineral dissolution significantly contributes to fluoride levels, while elevated nitrate may come from organic fertilizers.
- Spatial distribution analysis identified contamination hotspots, with 88% of groundwater samples exceeding safe fluoride and nitrate levels, posing particular health threats to vulnerable populations like teenagers and children.
Background: Using the sandwich osteotomy technique in the posterior mandible is delicate. This study aimed to assess the safety and the amount of bone gain using a full digital workflow versus the conventional procedure.
Patients And Methods: This split mouth study included 10 patients with bilateral vertically deficient posterior mandible.
Background And Objectives: Neonatal endotracheal tube (ETT) size recommendations are based on limited evidence. We sought to determine data-driven weight-based ETT sizes for infants undergoing tracheal intubation and to compare these with Neonatal Resuscitation Program (NRP) recommendations.
Methods: Retrospective multicenter cohort study from an international airway registry.
Factors that impact second attempt success for neonatal intubation following first attempt failure: a report from the National Emergency Airway Registry for Neonates.
Arch Dis Child Fetal Neonatal Ed
October 2024
Article Synopsis
- The study aimed to identify factors linked to successful second attempts at neonatal tracheal intubation and the risk of complications after a failed first attempt.
- Conducted in 18 academic NICUs using a large data set, it analyzed cases where neonates needed two or more intubation attempts from October 2014 to December 2021.
- Results showed that success rates for second attempts improved significantly when changes were made to the intubator, stylet use, or endotracheal tube size, with specific changes reducing the chances of severe desaturation.
Article Synopsis
- * Design: In a pilot crossover randomized controlled trial, 10 teams of three healthcare providers participated in two simulation setups (with and without ECG) to compare their performance, focusing on timing and frequency of pulse checks and other resuscitative actions.
- * Results: The study found that teams took significantly longer to check for a pulse and performed fewer pulse checks when using ECG monitoring, suggesting that ECG could lead to slower recognition of pulselessness and an over-reliance on the device, but did not affect other resuscitation steps.
Article Synopsis
- A new assessment tool called eXploring medical sTudents' caReer reAdiness (XTRA) has been created to evaluate medical students' preparation for their future careers using Super's career maturity theory.
- The instrument includes a 5-point Likert-scale and was tested on 348 students from 41 UK universities, showing good validity and reliability through various statistical analyses.
- XTRA demonstrated a positive correlation between students' self-rated career readiness and specific career planning factors, suggesting it could be useful for guiding and counseling medical students in their career development.
Article Synopsis
- - The study focused on translating the International Female Coital Incontinence Questionnaire (IFCI-Q) into Arabic (specifically for the Egyptian population) and validating its effectiveness for women who experience coital urinary incontinence (CI).
- - An expert panel translated the questionnaire, which was then tested for clarity and reliability among sixty patients divided into two groups: those with CI and those without, revealing significant differences in responses and high internal consistency (Cronbach's alpha between 0.9-1).
- - The validated Arabic IFCI-Q can be effectively used in various Arabic-speaking countries, helping improve the assessment of coital incontinence across different cultural and demographic groups.*
FTIR, H, and C NMR Characterization and Antibacterial Activity of the Combination of Euphorbia Honey and Potato Starch.
Comb Chem High Throughput Screen
July 2024
Article Synopsis
- Recent research focuses on creating innovative antibacterial hydrogels from potato starch and natural honey for use in wound dressings.
- The study utilized advanced techniques like FTIR and NMR spectroscopy to confirm the chemical structure and interactions of the components, revealing strong antibacterial properties.
- Findings indicate that the newly developed hydrogel exhibits significant antibacterial activity against key bacteria strains, suggesting its potential as an effective alternative to traditional antibiotics.
Article Synopsis
- * It highlights the importance of combining similarity scores of gene ontology terms to identify candidate genes, utilizing machine learning for classification and network analysis.
- * The study validates its findings through a case study on glomerular diseases, focusing on specific tissues and their gene expression patterns.
Over the past three decades, a notable rise in the occurrence of enteric protozoan pathogens, especially Giardia and Cryptosporidium spp., in drinking water sources has been observed. This rise could be attributed not only to an actual increase in water contamination but also to improvements in detection methods.
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- Synthetic mid-urethral slings (MUSs) are commonly used to treat female stress urinary incontinence, but there are concerns about serious complications from their use, leading to the exploration of alternative methods like the transobturator tension-free vaginal flap (TO-TVF).
- In a study involving 72 female patients, those undergoing TO-TVF showed improvement similar to those with conventional transobturator tape (TOT), with cure rates of 89% and 91.4% respectively, and no significant complications reported in either group.
- TO-TVF is suggested as a safe and effective surgical alternative to synthetic slings, utilizing natural tissue while potentially reducing risks associated with synthetic materials, though further long-term studies
Article Synopsis
- A study surveyed 2,159 North American neonatal health care professionals about their experiences, confidence, and training regarding the laryngeal mask airway (LMA), revealing significant gaps in knowledge and use.* ! -
- The majority of respondents had little to no clinical experience with the LMA, with 79% reporting no hands-on practice, and many doubting the adequacy of current training programs.* ! -
- Overall, neonatal HCPs showed low confidence and skill in using the LMA, suggesting a need for improved training and recognition of the device's importance as an alternative to endotracheal intubation.* !
Article Synopsis
- The study aimed to compare the effectiveness of simulation-based just-in-time training (JITT) versus a standard 5-minute video in teaching neonatal endotracheal intubation (ETI) skills to junior residents.
- Results showed that while both training methods had similar overall success rates, the simulation-based JITT led to a higher success rate on the first attempt and required less time for attempts.
- Although simulation-based JITT had some advantages, it also resulted in more mucosal trauma events, suggesting it should be used as a supplementary training method rather than a complete replacement.