Optimizing ventricular assist device rotor design parameters through computational fluid dynamics and design of experiments.

Heart failure is among the most widespread diseases globally. With the rapid rise in the number of affected individuals and the significant disparity between organ demand and supply, the relevance of implantable devices has grown each year. However, these devices face various regulatory restrictions, and obtaining approval requires outstanding performance.

Thermal Modeling of Polyamide 12 Powder in the Selective Laser Sintering Process Using the Discrete Element Method.

Selective laser sintering (SLS) is one of the key additive manufacturing technologies that can build any complex three-dimensional structure without the use of any special tools. Thermal modeling of this process is required to anticipate the quality of the manufactured parts by assessing the microstructure, residual stresses, and structural deformations of the finished product. This paper proposes a framework for the thermal simulation of the SLS process based on the discrete element method (DEM) and numerically generated in Python.

Analysis of shear stress related hemolysis in a ventricular assist device.

Background: Implantable devices such as ventricular assist devices provide appropriate treatment for patients with advanced heart failure. Unfortunately, these devices still have many problems, particularly related to blood damage.

Objective: The aim of this research is to examine two new ventricular assist devices in terms of induced shear stress, exposure time, and induced hemolysis.

Numerical study of a new ventricular assist device.

The present work presents a numerical study of two axial ventricular assist devices (VADs) with two different designs. The geometry of the first design was inspired by DeBakey's rotary blood pump and the geometry of the second design is based on BioCirc's pediatric VAD. The goal is to see which of the two designs has promising capabilities in terms of pressure differential, flow rate, and thrombosis before proceeding to deeper investigations.