Impact of platelet inhibition level on subsequent no-reflow in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.

Background: High P2Y platelet reactivity (PR) level after primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) affects prognosis and may induce the no-reflow phenomenon.

Aim: To investigate the role of PR in the genesis of microvascular obstruction.

Methods: Patients with STEMI undergoing PPCI within 12hours of symptoms onset were included prospectively.