Publications by authors named "Mourad Kourie"

Introduction: Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition associated with fibroinflammatory lesions that can occur at almost any anatomical site. It often presents as a multiorgan disease that may mimic malignancy, infection, or other immune-mediated conditions. Autoimmune pancreatitis (AIP) type 1 is the most prominent manifestation of IgG4-RD in the digestive tract, with common extra-pancreatic inflammation.

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Jaundice is an alarm symptom that should always be treated urgently, regardless of whether the responsible doctor is in primary care or in the emergency room. The differential diagnoses can be significantly delimited (hepatocellular vs. cholestasis) and several clues to the etiology can be determined from a carefully performed anamnesis, clinical examination, and basic laboratory tests.

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Article Synopsis
  • Chronic pancreatitis (CP) can present as either painful or painless, with a notable percentage (26.9%) of patients experiencing painless CP.
  • Painless CP patients are generally older at the time of diagnosis (61.7 years) compared to those with painful CP (52.5 years) and have a lower occurrence of alcoholic causes.
  • Both groups show similar rates of diabetes and pancreatic exocrine insufficiency, highlighting the need for regular monitoring of all CP patients, regardless of pain status.
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