The jujube honey from the Moroccan Middle Atlas area is thoroughly described in this study, which takes into account melissopalynological, physicochemical, antioxidant, mineral, and phytochemical characteristics. Twelve samples of jujube honey underwent in-depth analyses between 2019 and 2021. The honey's unifloral origin was confirmed by pollen analysis, which revealed that pollen predominated along with pollen from 21 other species.
View Article and Find Full Text PDFThe role of dietary vitamins and antioxidants in preventing colorectal cancer (CRC) is a significant area of research within nutritional oncology. However, the relationship between these nutrients and CRC prevention is complex and influenced by factors such as dosage, timing, and individual health status. This review aims to comprehensively analyze and synthesize the existing scientific literature on the potential role of dietary vitamins and antioxidants in preventing CRC.
View Article and Find Full Text PDFCardiovasc Hematol Disord Drug Targets
February 2024
Background: SARS-CoV-2 is a virus that uses ACE2 to enter the host cell.
Aims And Objectives: This study aimed to evaluate the in silico inhibitory activity of polyphenols from Prunus armeniaca (P. armeniaca) on angiotensin-converting enzyme 2 (ACE2).
Cardiovasc Hematol Disord Drug Targets
January 2022
Aims: The study aimed to evaluate the glucose-lowering effect of Tetraclinis articulata.
Background: Tetraclinis articulata is commonly used for the treatment of diabetes characterized by chronic hyperglycemia.
Objective: This work aimed to evaluate the effect of Tetraclinis articulata (T.
Curr Top Med Chem
September 2022
Ethnopharmacological Relevance: Plants of the genus Euphorbia have long been used as traditional medicine in China, Europe, America, Turkey, India, Africa, Iran, and Pakistan for their great medicinal value and health benefits. Their stems, leaves, roots, and latex are widely used to treat respiratory infections, body and skin irritations, digestive disorders, inflammatory infections, body pain, snake or scorpion bites, pregnancy, sensory disturbances, microbial and anticancer diseases.
Objectives: This review aims to provide updated information on the genus Euphorbia, including traditional medicinal uses, valuation and exploitation of medicinal plants, phytochemistry, botanical characterization, pharmacological and toxicological research focused on the medicinal properties of several Euphorbias in particular their antibacterial, anti-tumor, and cell manifestations, in addition to the effect of each isolated bioactive molecule from these species and their pharmacological use including preclinical evaluation of new drugs.
Cardiovasc Hematol Agents Med Chem
February 2023
Aims: The goal of this work was to evaluate the antihypertensive activity of Prunus armeniaca.
Background: Prunus armeniaca is known for its beneficial medicinal properties.
Objective: This study aimed to evaluate the effect of the aqueous extract of Prunus armeniaca L.
Endocr Metab Immune Disord Drug Targets
April 2023
Aims: The present study aimed to provide summarized data related to the phytocompouds improving glucose uptake in the diabetic state.
Background: Glucose uptake in peripheral tissues such as skeletal muscle and adipose tissue is considered as an important step in the regulation of glucose homeostasis. Reducing high blood glucose levels in diabetic patients via targeting peripheral glucose uptake is a promising strategy to develop new antidiabetic medications derived from natural products.
Cardiovasc Hematol Agents Med Chem
September 2022
Aims: The study aimed to assess the antihypertensive activity of Calamintha officinalis.
Background: Calamintha officinalis (CO) is a medicinal and aromatic herb as well as an antihypertensive plant that is widely used for its medicinal properties in several regions.
Objective: This study aimed to evaluate the effect of the aqueous extract of Calamintha officinalis (AECO) on vasorelaxant activity and arterial blood pressure under normal and hypertensive states in rats.
Cardiovasc Hematol Disord Drug Targets
February 2022
Aims: The study aimed to assess the antihyperglycemic activity of Pelargonium graveolens.
Background: Pelargonium graveolens (P. graveolens) (Geraniaceae) is a medicinal plant frequently used in traditional medicine in Morocco and Algeria as remedy against a multitude of illnesses.
J Environ Sci Health A Tox Hazard Subst Environ Eng
March 2022
As an alternative strategy in combating the COVID-19 pandemic, phytoconstituents from medicinal plants are getting attention worldwide. The current investigation focused on the efficacy of the essential phytocompounds identified in to target the main protease (M) of SARS-COV-2 through molecular docking and dynamic analyses; in addition to the safety assessment of this herb . , the 6LU7 structure of M was prepared as a target by Discovery Studio 2020.
View Article and Find Full Text PDFCardiovasc Hematol Disord Drug Targets
February 2022
Aims: The aim of the study was to evaluate the antihyperglycemic activity of propolis from Saharan region of Morocco.
Background: Propolis is known from ancient times for its beneficial action on health.
Objective: The study aimed to evaluate the effect of Moroccan propolis aqueous extract from the desert region on glycemia and lipid metabolism.
The existence of a causal relationship between the rise of the death rate in COVID-19 infected patients and their sufferance from non-communicable pathophysiological conditions, particularly chronic diseases, was recently evidenced. In fact, in addition to the immunodeficiency generated by chronic disease conditions, COVID-19 also led to affect the immune system. Furthermore, the novel coronavirus attacks the lungs and other vital organs such as heart, kidneys, and brain.
View Article and Find Full Text PDFEndocr Metab Immune Disord Drug Targets
December 2021
Aim: This study aimed to investigate the effect of Micromeria graeca on blood glucose levels and lipid parameters in an experimental model of diabetes.
Background: Micromeria graeca (L.) Benth.
Endocr Metab Immune Disord Drug Targets
August 2021
Aims: The present study was performed in order to analyze the antihypertensive activity of Micromeria graeca (L.) Benth. ex Rchb.
View Article and Find Full Text PDFEndocr Metab Immune Disord Drug Targets
June 2021
Objective: This study aimed to evaluate the effect of the aqueous extract of Anvillea radiate (A. radiata) aerial parts (AEAR) on arterial blood pressure in normotensive and hypertensive rats.
Methods: The effect of the acute and sub-chronic administration of AEAR on the following blood pressure parameters: systolic blood pressure (SBP), mean blood pressure (MBP), diastolic blood pressure (DBP), and heart rate (HR) was evaluated in normotensive and L-NAME induced hypertensive rats.
This review summarizes available data on argan fruit botany, geographical distribution, traditional uses, environmental interest, socioeconomic role, phytochemistry, as well as health beneficial effects and examination of future prospects. In particular, ethnomedical uses of argan fruits are carried out throughout Morocco where it has been used against various diseases. Different classes of bioactive compounds have been characterized including essential oils, fatty acids, triacylglycerols, flavonoids and their newly reported acylglycosyl derivatives, monophenols, phenolic acids, cinnamic acids, saponins, triterpenes, phytosterols, ubiquinone, melatonin, new aminophenols along with vitamin E among other secondary metabolites.
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