Background: Parasitic infection remains a serious health trade for humans and livestock. The purpose of this study was to present scientific proof of the anthelmintic properties of , which the native population uses to cure helminthiasis.
Method: Fresh eggs were isolated from faecal samples of experimentally infected mice.
Background: Helminthiasis is endemic in Chad and constitutes a public health problem, particularly among school-age children. The aim of this study was to evaluate the anthelmintic activity of extracts of and used in Chad by traditional healers for the treatment of helminthiasis.
Methods: The anthelmintic activity was assessed against and larvae using the Worm Microtracker.
Background: The spread of drug resistance is a significant issue, particularly in endemic countries with limited resources. The aim of this study was to evaluate antimalarial and antioxidant activity of in order to justify its use in traditional medicine.
Methods: Evaluation of the antimalarial activity of was carried out according to the model of the suppressive and curative test of Peters' over 4 days in infected mice.
Background: Cerebral malaria is one of the most severe and dangerous forms of malaria and is potentially fatal. This study was aimed at evaluating the anticerebral malaria efficacy of used by traditional healers.
Method: Fifty grams of stem bark was macerated in 1 L ethanol (95%) for 72 h.
Background: Infections with gastrointestinal helminths constitute a serious obstacle to the good health of the local population in most African Countries. The aim of this study was to evaluate the anthelminthic activity of ethanol and aqueous extracts against using the worm microtracker.
Method: Aqueous and ethanolic extracts of were prepared.
Background: Malaria remains a major public health problem in the tropical and subtropical regions. This study aimed of investigating the antimalarial and antioxidant activities of ethanol extract of stem bark. .
View Article and Find Full Text PDFBackground: Reduction of oxidative stress during malaria infection is considered as being of great benefit so long as treatment and drug development approaches are concerned. This study had the aim of evaluating the antimalarial and antioxidant activities of the ethanolic extract of in Swiss albino mice infected with the NK65 strain.
Methods: the antiplasmodial activity of the plant ethanolic extract was tested in a four-day suppressive and curative assay using in Swiss albino mice.
Introduction: Resistance to common antimalarial drugs and persistence of the endemicity of malaria constitute a major public health problem in Cameroon. The aim of this study was to evaluate the antiplasmodial, antioxidant, and cytotoxic activities of aqueous and ethanol extracts of used by Cameroonian traditional healers for the treatment of malaria.
Methods: Aqueous and ethanolic stem bark extracts were prepared according to standard procedures.
Background: Malaria is a serious public health problem, especially in sub-Saharan Africa. The aim of this study was to scientifically provide baseline information on the use of stem bark as an antimalaria drug by traditional healers.
Method: The stem barks of were harvested and dried to obtain powder, and fifty grams of the powder were soaked in ethanol and hot distilled water respectively, for the preparation of ethanol and aqueous extracts, then dried in an oven at 40°C for the ethanol extract and 50°C for the aqueous extract.
Background: Malaria is the leading cause of morbidity and mortality in African countries. We aimed this study at evaluating the antiplasmodial, antioxidant, and cytotoxicity activity of extracts.
Method: The aqueous and ethanol extracts were obtained by maceration.
Background: There are about 13 parasitic infections that are responsible for significant morbidity and mortality but have not received the attention they deserve; thus, they are now known as "neglected tropical diseases" (NTDs). This study was aimed at evaluating the antihelminthic activities of using an automated high-throughput method.
Methods: The antihelminthic activity effect of the extracts against .
Background: One of the most dangerous Plasmodium species is . Hence, it causes a higher rate of mortality. The resistance of to the ACT (Artemisinin-based Combination Therapies) has led to the search for new antimalarial drugs.
View Article and Find Full Text PDFBackground: Malaria is one of the most critical diseases causing about 219 million cases worldwide in developing countries. The spread and development of resistance against chemical antimalarial drugs is one of the major problems associated with malaria control. The present study was to investigate the antimalarial efficacy of ethyl acetate extract and one fraction of in order to support the usage of this plant by traditional healers to treat malaria.
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