Publications by authors named "Mounika Thirunagari"

Article Synopsis
  • * This systematic review evaluates the effectiveness of semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), in non-diabetic individuals, focusing on weight loss, waist circumference, and the percentage of participants achieving at least a 5% weight reduction.
  • * The review analyzed 10 quality studies, including nine randomized control trials, involving 6,623 participants, and concluded that semaglutide is an effective weight-loss medication for obese or overweight non-diabetic populations, providing valuable insights for obesity treatment strategies.
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Resistant hypertension is blood pressure (BP) that is persistently above target in spite of the maximally tolerated usage of at least three anti-hypertensives simultaneously. The sympathetic nervous system is instrumental in blood pressure (BP) regulation. Renal (sympathetic) denervation involves using ablative energy to disrupt the sympathetic nerves in renal arteries.

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Article Synopsis
  • * Treatment options for CS include corticosteroids as the primary choice, along with immunosuppressive agents, biological therapies for hard-to-treat cases, and standard heart failure medications to support cardiac function.
  • * A systematic review was conducted following PRISMA guidelines, analyzing recent research on heart failure caused by sarcoidosis, narrowing down from 36,755 articles to 11 high-quality studies for evaluation.
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