Selective expression of KCNA5 and KCNB1 genes in gastric and colorectal carcinoma.

Background: Gastric and colorectal cancers are the most common malignant tumours, leading to a significant number of cancer-related deaths worldwide. Recently, increasing evidence has demonstrated that cancer cells exhibit a differential expression of potassium channels and this can contribute to cancer progression. However, their expression and localisation at the somatic level remains uncertain.

Acute Gangrenous Cholecystitis: Proposal of a Score and Comparison with Previous Published Scores.

Background: Gangrenous cholecystitis (GC) is a particularly severe form of acute cholecystitis (AC) and is associated with an increased risk of postoperative morbidity and mortality. Recent reports show that surgeons are remarkably unsuccessful in diagnosing GC.

Methods: We conducted a retrospective study involving 587 patients with AC.