This study focuses on identifying active compounds within Chenopodium ambrosioides extracts and fractions, with a specific emphasis on their potential analgesic and antidiabetic properties. The motivation arises from the reported therapeutic effects of the plant and the desire to pinpoint the compounds responsible for these benefits. Gas chromatography-mass spectrometry spectrophotometric analysis was employed to characterize chemical constituents in the aqueous extracts (infused aqueous extract and macerated aqueous extract) and fractions (cyclohexane fraction, ethyl acetate fraction, butanol fraction, remaining aqueous fraction) of C.
View Article and Find Full Text PDFBackground: Trastuzumab (Herceptin®) is currently the main treatment option for breast cancer patients that overexpress the human epidermal growth factor receptor 2 (HER2). This antibody binds specifically to HER2, blocks cancer cell growth, and promotes effective cell death. In the present study, we sought to develop a robust and efficient process for the development of a stable Chinese hamster ovary (CHO) cell line with high trastuzumab expression and production.
View Article and Find Full Text PDFObjectives: Moroccan is an essential medicinal plant; however, little is known about the biological properties of its leaves mentioned in Moroccan traditional medicine.
Methods: Various standard experiments were performed to evaluate the phytochemical, antidiabetic, antioxidant, antibacterial, and acute and sub-chronic toxicity characteristics of leaves.
Results: Phytochemical screening led to the identification of several phytochemical classes, including tannins, flavonoids, terpenoids, and anthraquinones, with high concentrations of polyphenols (31.
The objectives of this work were to determine the phytochemical composition and antioxidant, anti-diabetic, antibacterial, anti-inflammatory, and anti-acetylcholinesterase properties of L. and L. EOs.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
June 2022
Moroccan folk healers use medicinal plants to treat several diseases including skin burns. The traditional knowledge of wound healing is not common among the general population. Only one ethnobotanical survey was carried out in Rabat, Morocco, to track the traditional use of medicinal plants in wound healing.
View Article and Find Full Text PDFEthnopharmacological Relevance: Arbutus unedo L., (Ericaceae) is one of the most traditional plants commonly used to treat diabetes in people living in Eastern Morocco region particularly in Taza and Beni Mellal.
Aim Of The Study: The aim of the study was to find if there is a scientific support to the ethnopharmacological relevance use of Arbutus unedo L.
Objectives: Diabetes is one of the most life-threatening chronic metabolic disorders and is considered a global health problem due to its prevalence and incidence. In Morocco, several herbal preparations are utilized to treat this disease. For this reason, the current study aimed to identify and to collect data about the medicinal plants utilized in folk medicine for the treatment of diabetes in the Beni Mellal region of Morocco.
View Article and Find Full Text PDFAim Of The Study: Nigella sativa L. (Ranunculaceae) seeds have been used traditionally for centuries, notably for treating diabetes.
Materials And Methods: We studied the effects of the crude aqueous extract of Nigella sativa seeds on intestinal glucose absorption in vitro using a short-circuit current technique and in vivo using an oral glucose tolerance test.