Background: Empathy is a crucial attribute in healthcare, benefiting both professionals and patients. It also plays an important role in the midwife-woman relationship, contributing to the implementation of respectful maternity care. Witnessing acts of disrespect towards childbearing women in the clinical setting may impair students' perceptions of respectful maternity care, as they may come to view disrespect as normative.
View Article and Find Full Text PDFA prelithiated Sn (LiSn) anode was developed for sulfide-based all-solid-state Li batteries (ASSLBs), demonstrating high compatibility with LiPSCl sulfide electrolyte. The LiSn|NCM811 cell achieved 163 mA h g capacity (0.1C) and 91% retention after 650 cycles (1C).
View Article and Find Full Text PDFHydrogen sulfide (H2S) is increasingly recognized as a crucial signaling molecule in plants, playing key roles in regulating physiological processes and enhancing stress tolerance. This review provides an updated summary of H2S signaling in plant stress responses, discussing its uptake from external environmental sources, its endogenous biosynthesis, and its broader functions in stress adaptation. We summarize the impact of H2S on plants under various stress conditions and review the mechanisms through which it mediates signaling functions, with a particular focus on H2S-mediated protein persulfidation.
View Article and Find Full Text PDFCurrent high-sensitivity immunoassay protocols often involve complex signal generation designs or rely on sophisticated signal-loading and readout devices, making it challenging to strike a balance between sensitivity and ease of use. In this study, we propose a homogeneous-based intelligent analysis strategy called Mata, which uses weight analysis to quantify basic immune signals through signal subunits. We perform nanomagnetic labeling of target capture events on micrometer-scale polystyrene subunits, enabling magnetically regulated kinetic signal expression.
View Article and Find Full Text PDFCombined solid electrolytes address cathode-anode compatibility in all-solid-state Li-ion batteries (ASSLBs), yet interface stability and ion transport mechanisms between different electrolytes remain unclear. Herein, we investigate LiPSCl (LPSC), LiInCl (LIC), and LiZrOCl (LZOC) composite electrolytes through electrochemical analysis and operando X-ray photoelectron spectroscopy. Our results reveal that the electrostatic potential difference between LPSC and LIC inhibits Li migration, leading to the decomposition of LIC into InCl and LiCl, causing battery failure.
View Article and Find Full Text PDFBTB and CNC homology 1 (Bach1) is a transcription factor that mediates oxidative stress and inflammation and participates in the progression of diseases such as atherosclerosis, colitis, and acute lung injury. In this study, we aimed to explore the role of Bach1 in radiation pneumonitis (RP) and elucidate its underlying mechanism. Bach1 expression was significantly elevated in the lung tissues of RP mice.
View Article and Find Full Text PDFIntroduction: Postoperative pancreatic fistula (POPF) is the most severe complication after pancreaticoduodenectomy (PD), and this study investigates the effects of single-layer and double-layer pancreaticojejunostomy (PJ) on POPF.
Evidence Acquisition: Four electronic databases were systematically searched until March 2024: PubMed, Web of Science, Embase, and Cochrane Library. Statistical analysis was performed using Review Manager (RevMan) software.
The structure feature determines its performance. In the field of biological implants, microlattices are commonly used as building blocks for light-weight and adaptive purposes, which however show limitations in biological and mechanical properties as compared with natural bones. Inspired by the efficient mass transfer and high fault tolerance of biological neural networks derived from the hierarchical structure and functional gradient, a bioinspired paste-extrusion printed microlattice (BPPM) structure is developed and its tunable properties are demonstrated.
View Article and Find Full Text PDFTesting diverse biomolecules and observing their dynamic interaction in complex biological systems in a label-free manner is critically important for terahertz (THz) absorption spectroscopy. However, traditionally employed micro/nanophotonic techniques suffer from a narrow operating resonance and strong absorption band interference from polar solutions preventing seriously reliable, on-demand biosensor integration. Here, a multifunctional THz plasmonic biosensing platform by leveraging multiple interfering resonances from quasi-bound states in the continuum designed to noninvasively and in situ track the temporal evolution of molecules in multiple analyte systems, is proposed.
View Article and Find Full Text PDFThe traditional trial-and-error approach, although effective, is inefficient for optimizing rubber composites. The latest developments in machine learning (ML)-assisted methodologies are also not suitable for predicting and optimizing rubber composite properties. This is due to the dependency of the properties on processing conditions, which prevents the alignment of data collected from different sources.
View Article and Find Full Text PDFHigh-performance signal processing and telecommunication systems absolutely necessitate analog-to-digital converters (ADCs) that offer extensive bandwidth, exceptional precision, and minimal power consumption, in order to efficiently convert real-world analog signals into digital signals. While current electronic ADCs are constrained by limitations such as low bandwidth, high jitter noise, susceptibility to electromagnetic interference, and excessive energy consumption, photonic ADCs present promising solutions to overcome these challenges. Here, a programmable photonic ADC is developed by integrating phase-change materials (PCMs) with silicon photonics fabricated using foundry processes.
View Article and Find Full Text PDFOxide interfaces have enormous potential for future electronics with many applications, such as large spin Hall conductance, phase transitions, topological states, and superconductivity. However, previous investigations have predominantly focused on gigahertz frequencies; whilst the possibilities to fabricate devices operational at terahertz frequencies are demonstrated. A model solution is proposed employing 5d rare-earth, strontium iridate (SrIrO) heterostructure with cobalt (Co) ultrathin layers.
View Article and Find Full Text PDFGenetic characterization including Southern blot analysis of recombinant Chinese hamster ovary (CHO) cell lines expressing biologics is an essential prerequisite for regulatory submissions. The transposon-based expression system for CHO cell lines enables the insertion of DNA sequences into the genome and has been widely used by the biopharmaceutical industry. The system yields clones that are both highly productive and genetically stable.
View Article and Find Full Text PDFEnviron Sci Technol
March 2025
With the upcoming transition to clean electric vehicles, the sources of volatile organic compounds (VOCs) in the ambient environment are rapidly changing and highly uncertain. Here, through systematic characterization of emissions from a typical apartment in a Chinese megacity (Shenzhen), we show that indoor environments contribute significantly to the levels of ambient (i.e.
View Article and Find Full Text PDFCompared to the traditional slurry-coating process, the solvent-free manufacturing process holds significant potential due to its advantages, including economic viability, thick electrodes, and avoidance of organic solvents. However, the currently dominant solvent-free process suffers from poor mechanical properties and electrochemical instability. Herein, a conductive binder (M@EP), composed of multi-walled carbon nanotubes (MWNT) and epoxy resin-based binders (EP), is designed and synthesized.
View Article and Find Full Text PDFVinyl sulfonates are vital intermediates in organic synthesis, serving as versatile electrophiles in various cross-coupling reactions. Despite their significance, direct methods for synthesizing vinyl sulfonates from styrenes have been limited. In this study, we introduce an innovative electrochemical approach that leverages bromine radical mediation to facilitate the direct synthesis of vinyl sulfonates, cheap BuNBr acts as both an electrolyte and a catalytic amount.
View Article and Find Full Text PDFMultifunctional photodetectors have driven the development of traditional optical communication technologies and emerging artificial intelligence fields. While three-dimensional (3D) organic lead trihalides have recently demonstrated potential as versatile photodetectors, the device performance is constrained by ion mobility limitations. In contrast, low-dimensional metal halide perovskites (MHPVKs) exhibit enhanced intrinsic stability, suppressed ion migration, and exceptional photoelectric properties.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
March 2025
This study explores two structurally related π-skeletons. The π-skeleton of compounds 1a-e containing three heptagons represents a key fragment in theoretical carbon schwarzites, while that of 2a-b is a triple [6]helicene. Compounds 1a-e were synthesized via Scholl reactions, and using a weaker acid allowed the reaction to stop at an intermediate stage, yielding 2a-b.
View Article and Find Full Text PDFThe electrocatalytic nitrate reduction to hydroxylamine (NHOH) is a challenging catalytic process that has gained significant attention. However, its performance is hindered by the low selectivity of the electrocatalysts. Here, intermetallic PtSn nanosheets with p-d orbital hybridization have been synthesized, which significantly enhances the performance of electrocatalytic nitrate reduction to NHOH.
View Article and Find Full Text PDFCurr Pharm Biotechnol
March 2025
Ultrasound is an indispensable technology in the biomedical field. With the continuous integration and development of ultrasound medical technology, its potential application value in disease diagnosis and treatment has become increasingly prominent. As the technical core, novel multifunctional ultrasound theranostic agents have been the main focus of research.
View Article and Find Full Text PDFTrop2 exhibits significantly elevated expression in numerous solid malignancies, playing a crucial role in tumor advancement, whereas its presence in healthy tissues is minimal. In this study, we investigated Trop2 expression in bladder cancer models using [Cu]Cu-NOTA-Trodelvy for immunoPET imaging. In HT-1376 models, [Cu]Cu-NOTA-Trodelvy effectively visualized tumor as early as 12 h p.
View Article and Find Full Text PDFSalinity is a major abiotic stress that adversely affects rice growth and production. However, the detailed regulatory mechanisms of salt stress response in rice remain largely unexplored. In this study, we established that the RING-type E3 ubiquitin ligase OsRFI2 plays a negative role in salt tolerance in rice.
View Article and Find Full Text PDFRecent studies have highlighted the progress of robotic-assisted radical cystectomy (RARC), yet information on intracorporeal (ICUD) and extracorporeal urinary diversion (ECUD), especially in elderly patients, remains limited. This review seeks to address this gap in the literature. A systematic literature review was conducted in PubMed, Embase, Web of Science, and Cochrane Library databases, following the PRISMA guidelines.
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