Publications by authors named "Mouhamed Amr Sabouni"

Article Synopsis
  • * A meta-analysis of nine randomized controlled trials (RCTs) from 2003 to 2023 revealed that CETPis significantly reduced cardiovascular disease (CVD)-related mortality and the risk of myocardial infarction, particularly with the drug anacetrapib.
  • * Despite the positive effects on CVD-related mortality and myocardial infarction, CETPis did not show improvements in other cardiovascular outcomes, indicating mixed results in their overall efficacy.
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Mechanical circulatory support devices are used to support the heart in cardiogenic shock. We present a case of demonstrating the feasible use of left ventricular assistive device with reverse configuration to support severe right ventricular failure in a patient with recent tricuspid annuloplasty ring.

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Cardiac tamponade is a life-threatening complication during left atrial appendage (LAA) closure. We report a 77-year-old woman who underwent a transseptal puncture for LAA closure with the Watchman device that was complicated by tamponade. This was successfully treated with the deployment of a Cardioform 25-mm septal occluder device.

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Although it is no longer in production, the Starr-Edwards valve has successfully replaced hundreds of thousands of heart valves in the past 50 years of its use. We report on the case of a valve in the aortic position still functioning 49 years after implantation without replacement, showcasing the valve's durability.

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The frequency of 18q- is estimated to be approximately 1/40 000 live births and is more commonly associated with certain clinical features including short stature, intellectual disability and malformations of many major organ systems. Congenital cardiac abnormalities are present in 24-36% of cases and screening can prove difficult. A 28-year-old Caucasian female with a history of long arm chromosome 18q deletion was evaluated for persistent dyspnea and decreased activity level.

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Purpose Of Review: The need for liver transplant due to the progression of hepatitis C virus (HCV) infection necessitates the consideration of antiviral treatment. Host genomic variations affect response to HCV treatment and predict the rates of adverse effects. Recently, multiple genomic polymorphisms were found to be critical in predicting treatment response as well as the rate of neuropsychiatric adverse effects in patients infected with HCV who are receiving antiviral treatments.

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Synopsis of recent research by authors named "Mouhamed Amr Sabouni"

  • - Mouhamed Amr Sabouni's research focuses on cardiovascular health, with a specific interest in the mechanisms and interventions related to cholesterol management, particularly through the lens of Cholesteryl Ester Transfer Protein inhibitors and their potential impact on cardiovascular outcomes.
  • - His work also delves into innovative approaches and case studies in cardiac procedures, such as the use of a Cardioform Septal Occluder for treating cardiac tamponade and exploring mechanical circulatory support configurations for right ventricular failure management.
  • - Additionally, Sabouni has investigated the genetic factors influencing hepatitis C treatment responses, contributing to personalized medicine by identifying genomic polymorphisms that affect therapeutic outcomes and side effects.