- Pancreatic β-cell transplantation is a promising therapy for type I diabetes, but is limited by a shortage of human pancreas donors, driving research into stem cell alternatives for insulin-producing cells.
- The study created a novel MXene composite nanofibrous scaffold to support the growth and differentiation of stem cells into pancreatic β-cells, demonstrating superior properties like a porous structure and increased hydrophilicity.
- Results showed that stem cells grown on the MXene scaffold developed stronger characteristics of pancreatic β-cells and produced more insulin in response to glucose, suggesting this approach could improve diabetes treatments.