Publications by authors named "Motonori Kano"
Neisseria gonorrhoeae is one of the important pathogens of sexually transmitted infections. N. gonorrhoeae is rapidly becoming antimicrobial resistant, and there are few drugs that are effective in the initial treatment of gonorrhea.
View Article and Find Full Text PDFNationwide surveillance of the antimicrobial susceptibility of Chlamydia trachomatis from male urethritis in Japan: Comparison with the first surveillance report.
J Infect Chemother
January 2022
Article Synopsis
- The Urogenital Sub-committee and Surveillance Committee of various Japanese health organizations conducted a nationwide study to assess how susceptible Chlamydia trachomatis is to different antibiotics by collecting clinical samples from 26 hospitals between May 2016 and July 2017.
- The study measured the minimum inhibitory concentrations (MICs) for a range of antibiotics, finding no resistant strains to fluoroquinolones, tetracyclines, or macrolides, while solithromycin showed particularly favorable MIC values.
- However, the MIC for azithromycin was slightly higher than in previous reports, suggesting the need for ongoing monitoring of its susceptibility.
Article Synopsis
- * A surveillance study conducted in Japan collected urethral discharge samples from patients in 2009 and 2012 to test for antibiotic resistance in C. trachomatis isolates.
- * Results showed that no resistant strains were found against common antibiotics like fluoroquinolones, tetracyclines, or macrolides during both years of the study.
Worldwide, the most important concern in the treatment of sexually transmitted infections is the increase in antimicrobial resistant Neisseria gonorrhoeae strains including resistance to cephalosporins, penicillins, fluoroquinolones or macrolides. To investigate the trends of antimicrobial susceptibility among N. gonorrhoeae strains isolated from male patients with urethritis, a Japanese surveillance committee conducted the second nationwide surveillance study.
View Article and Find Full Text PDFNationwide surveillance of bacterial pathogens from patients with acute uncomplicated cystitis conducted by the Japanese surveillance committee during 2009 and 2010: antimicrobial susceptibility of Escherichia coli and Staphylococcus saprophyticus.
J Infect Chemother
June 2013
Article Synopsis
- A nationwide surveillance study conducted in Japan from April 2009 to November 2010 examined antimicrobial susceptibility patterns of uropathogens causing acute uncomplicated cystitis in women, involving 43 hospitals.
- The study identified E. coli as the most common bacteria (77.8%) in urine samples, with significant occurrences of S. saprophyticus in premenopausal women, while also analyzing their resistance to 19 antimicrobial agents.
- Results indicated high susceptibility of E. coli to fluoroquinolones and cephalosporins, but a rising trend in fluoroquinolone-resistant and ESBL-producing strains highlights the need for careful selection of empirical treatments based on patient characteristics.
Objective: To assess the functional results, health-related quality of life (QOL) outcomes, and complications in patients with an ileal neobladder in comparison to those with cutaneous diversion (ileal conduit and cutaneostomy).
Methods: Between September 1992 and February 2003, we consecutively performed an ileal neobladder (the Studer method) in 30 patients and cutaneous diversion in 38 patients. In August 2004, questionnaires were mailed to 54 patients.
An examination of the change in plasma concentration of OH-flutamide in low-dose flutamide (250 mg/day) monotherapy for 5 prostate cancer patients was performed. We treated 5 patients diagnosed with prostate cancer between September and November 2002. The plasma concentrations of OH-flutamide, PSA and AST/ALT were measured before and after low-dose flutamide monotherapy was started.
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