Publications by authors named "Motoko Sei"

Article Synopsis
  • This study investigates how fluctuations in body mass index (BMI) and waist circumference (WC) affect remission rates of metabolic dysfunction-associated fatty liver disease (MAFLD) across genders.
  • Analyzed data from 1,823 MAFLD patients revealed that men who decreased their BMI and WC variability showed significantly higher remission odds, while women benefited from healthy lifestyle habits like exercise and eating breakfast.
  • The findings suggest that targeting BMI and WC reduction in men, along with promoting lifestyle changes in women, could help improve remission rates for MAFLD.
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Article Synopsis
  • The study aimed to explore the relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) and erosive esophagitis (EE), as the link was not well understood.
  • It analyzed data from 1,578 patients over two years, finding that men had a higher rate of developing EE compared to women, with specific odds ratios indicating a correlation between MASLD and EE in men and older individuals.
  • The results highlighted that risk factors for developing EE varied based on sex and age, particularly emphasizing that those aged 50 and older with multiple MASLD components are at an increased risk for developing EE.
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Background And Aim: The influence of metabolic dysfunction-associated fatty liver disease on gallstone development remains unclear. We aimed to investigate the longitudinal association between metabolic dysfunction-associated fatty liver disease and gallstone development in both men and women.

Methods: This observational cohort study included 5398 patients without gallstones who underwent > 2 health check-ups between April 1, 2014, and March 31, 2020.

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Acquired factor V deficiency is a rare disease that presents with various bleeding symptoms because of the acquired production of factor V inhibitors and decrease in factor V activity. We have experienced five cases of acquired factor V deficiency diagnosed on the basis of abnormalities in coagulation tests in the last 10 years. All five patients were older men, of whom one had no bleeding symptoms, and three had a history of renal failure and malignant tumors.

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