Publications by authors named "Motokazu Nishikado"
J Pediatr Hematol Oncol
May 2022
Article Synopsis
- - Anemia without a clear cause can often delay the diagnosis of idiopathic pulmonary hemosiderosis (IPH) in children, which is a condition that affects the lungs.
- - A 5.8-year-old girl initially presented with iron-refractory iron deficiency anemia and was later diagnosed with IPH at 6.8 years old after showing specific symptoms and having hemosiderin-laden alveolar macrophages identified in her gastric aspirate.
- - While diagnosing IPH usually takes between 16 to 30 months, this particular case took 12 months from the first signs of anemia to reach the IPH diagnosis.
Article Synopsis
- A female neonate was found to have severe hypofibrinogenemia (<50 mg/dL) shortly after birth, raising concerns about potential hemorrhage despite her not showing any immediate symptoms.
- To prevent bleeding, she received fresh frozen plasma (FFP) treatment twice a week to maintain safer fibrinogen levels.
- Genetic testing later revealed a novel mutation in her fibrinogen genes, indicating a diagnosis of congenital hypofibrinogenemia, and her treatment was concluded by two months of age when she remained asymptomatic.
