Optic nerve decompression for orbitofrontal fibrous dysplasia.

Orbitofrontal fibrous dysplasia often involves the bony orbit and the optic canal. Although fibrous dysplasia reportedly produces compression of the optic nerve leading to visual distrubances, optic nerve decompression in patients without clinical signs of optic neuropathy is still controversial. We describe two patients with orbitofrontal fibrous dysplasia without signs of visual disturbance and one patient with McCune-Albright syndrome and progressive visual impairment.

Sumatriptan scavenges superoxide, hydroxyl, and nitric oxide radicals: in vitro electron spin resonance study.

Background: The molecular mechanisms of migraine have not yet been clarified. Oxygen free radicals have been implicated in the genesis of many pathological processes, including migraine. Sumatriptan succinate is known to be a very effective drug for acute relief of migraine attack.

Male prolactinoma with pituitary apoplexy concomitant with intracerebral hemorrhage--case report.

A 56-year-old male presented with a prolactin-secreting pituitary adenoma who suffered pituitary apoplexy associated with intracerebral hemorrhage of the caudate head and putamen. The centers of both the intratumoral hematoma and intracerebral hemorrhage appeared as hyperintense on T1-weighted and T2-weighted magnetic resonance imaging, indicating the subacute stage and probably similar timing of onset. The tumor was treated surgically 6 weeks after the onset.