Investigation of integron classes 1, 2, and 3 among multi-drug resistant Staphylococcus aureus isolates in Iran: a multi-center study.

Background: Rising methicillin-resistant Staphylococcus aureus (MRSA) poses a global health threat, contributing to serious infections with high mortality rates. Integrons are recognized as significant genetic elements in disseminating multidrug-resistant (MDR) strains. This study focuses on assessing the prevalence of integron classes 1, 2, and 3 in S.

Study of MIC of silver and zinc oxide nanoparticles, strong and cost-effective antibacterial against biofilm-producing Acinetobacter baumannii in Shiraz, Southwest of Iran.

Background: Acinetobacter baumannii resistant strains lead to increased mortality, treatment costs, and an increase in the length of hospitalization. Nowadays, nanoparticles are considered a substitute for antibiotics. This study aimed to determine the MIC of Silver (Ag) and Zinc Oxide (ZnO) Nanoparticles (NPs) on Biofilm-Producing Acinetobacter baumannii and determine the relationship between MIC and frequency of efflux pump genes in cutaneous specimens in Shiraz, Southwest Iran in 2021-2022.

Anomalous behavior in entanglement speed profile through spin chains.

The origin of the uniform Dzyaloshinskii-Moriya interaction (DMI), which is responsible for the creation of chiral magnetism, has been the subject of extensive research. Recently, modern technology has allowed for its production and utilization in a modulated form. Not only can magnetic phases of spin chains be enriched by the presence of such a potential as detailed in Japaridze et al.

Evaluating antimicrobial activity and cytotoxicity of silver nanoparticles incorporated into reinforced zinc oxide eugenol: an in vitro study.

Purpose: This study aimed to evaluate the antibacterial and cytotoxic effects of reinforced zinc oxide-eugenol (rZOE) incorporated with different concentrations of silver nanoparticles (AgNPs).

Methods: The pastes of rZOE alone or mixed with AgNPs at concentrations of 1%, 2%, and 5% of weight were prepared. In vitro antimicrobial activity of prepared materials against Streptococcus (S.

COVID-19 in patients with anemia and haematological malignancies: risk factors, clinical guidelines, and emerging therapeutic approaches.

Extensive research in countries with high sociodemographic indices (SDIs) to date has shown that coronavirus disease 2019 (COVID-19) may be directly associated with more severe outcomes among patients living with haematological disorders and malignancies (HDMs). Because individuals with moderate to severe immunodeficiency are likely to undergo persistent infections, shed virus particles for prolonged periods, and lack an inflammatory or abortive phase, this represents an overall risk of morbidity and mortality from COVID-19. In cases suffering from HDMs, further investigation is needed to achieve a better understanding of triviruses and a group of related variants in patients with anemia and HDMs, as well as their treatment through vaccines, drugs, and other methods.

Association of polymorphism of IL-17A, IL-17F, and IL-6 with Toxoplasma gondii infection susceptibility in HIV/AIDS patients in Shiraz, southern Iran.

Introduction: Toxoplasma gondii infection is considered as one of the most important opportunistic infections and cause of death in HIV patients.

Methods: In this cross-sectional study, 334 HIV positive patients were included. The molecular test was performed by the restriction fragment length polymorphism-polymerase chain reaction method.

Relationship between interleukin 17 polymorphism in rs 2275913 and rs 763780 and interleukin 6 in rs 1800795 gene region with sensitivity to antiretroviral drugs in patients with human immunodeficiency virus.

Drug complication is still considered as one of the most important causes of death and drug in-compliance around the world. In this cross sectional study, 372 people living with HIV (PLHIV) above 16 years were enrolled. The drug complication was extracted based on the information of the patient's file.

The role of periodontitis-associated bacteria in Alzheimer's disease: A narrative review.

Alzheimer's disease causes memory loss and dementia in older adults through a neurodegenerative mechanism. Despite the pathophysiological clarification of this cognitive disorder, novel molecular and cellular pathways should be identified to determine its exact mechanism. Alzheimer's disease (AD) is pathologically characterized by senile plaques comprising beta-amyloid and neurofibrillary tangles (NFTs) formed by hyperphosphorylated tau as a microtubule-associated protein with a key role in the pathogenesis of AD.

Detection of genes encoding enterotoxins (SEA-D) in strains isolated from workers' nasal samples and creamy pastries of Shiraz confectioneries.

Background And Objectives: is responsible for the majority of food poisoning all around the world. Nasal carriers of and foodstuffs need for handling are important sources and vehicles to transmit this pathogen to ready-to-eat foods. According to hygienic standards, confectioners should not be contaminated with This study aimed to detect nasal carriers and creamy pastries contaminated with enterotoxigenic in confectioneries of Shiraz, Iran.

Genotypic evaluation of isolated from cattle and sheep by pulsed-field gel electrophoresis.

a Gram-negative bacterium exists as a commensal in the upper respiratory tracts of livestock, and poultry. It is causative agent of a range of diseases in mammals and birds including fowl cholera in poultry, atrophic rhinitis in pigs and bovine hemorrhagic septicemia in cattle and buffalo. This study aimed to isolate from sheep and cattle lungs sampled and assessed by bacteriological procedures and pulse field gel electrophoresis (PFGE) characterization.

Entanglement transmission due to the Dzyaloshinskii-Moriya interaction.

We revisited the effectiveness of state and entanglement transmission through a spin-chain-based quantum channel while altering the system parameters and the channel's initial state. Our research is focused on the spin-1/2 XX chain with Dzyaloshinskii-Moriya (DM) interaction and the aim is to measure entanglement dynamics between different part of the chain. The speed of entanglement propagation is utilized to probe the evolution of the system via three scenarios: (i) pure Heisenberg interaction, (ii) pure DM interaction, and (iii) collaboration of both types of couplings.

High-Level Resistance to Aminoglycosides Among Multidrug Resistant Non-faecalis and Non-faecium Enterococci.

Background: Enterococci are considered as important causative pathogens of a variety of community and hospital-acquired infections. Due to the development of multidrug resistant (MDR) enterococci and the emergence of strains possessing high-level resistance to antimicrobial agents, treatment of their infections has been more complicated. In addition to more prevalent species of the Enterococcus genus, non-faecalis/non-faecium species are also responsible for severe healthcare-associated infections.

Virulence factors, serogroups, and antibiotic resistance of Shiga-toxin producing from raw beef, chicken meat, and vegetables in Southwest Iran.

Background: Shiga-toxin-producing (STEC) is an important food-borne pathogen causing human diseases with severe symptoms. Although the O157 serotype has been mostly isolated from human specimens, the increasing incidence rates of non-O157 serogroups have attracted special attention in recent years.

Aims: Evaluation of the epidemiology and identification of different characteristics of STEC isolates from raw beef, chicken meat, and vegetable samples in Shiraz, Southwest Iran.

The effect of photodynamic therapy by gold nanoparticles on Streptococcus mutans and biofilm formation: an in vitro study.

In this experimental study, we aimed to evaluate the antibacterial and anti-biofilm effects of photodynamic therapy with a photosensitizer in conjunction with Gold nanoparticles against Streptococcus mutans as an important cariogenic bacterial agent. This experimental in vitro study evaluated the antibacterial and anti-biofilm effect of five groups as followed against S. mutans: methylene blue (MB), Gold nanoparticles (AuNPs), methylene blue conjugated with Gold nanoparticles (MB-AuNPs), MB mediated photodynamic therapy (MB mediated PDT) and methylene blue conjugated with Gold nanoparticles mediated photodynamic therapy (MB-AuNPs mediated PDT).

Disinfection of dentinal tubules with diclofenac sodium and N-Acetylcysteine compared with calcium hydroxide as intracanal medicaments against Enterococcus faecalis.

The purpose of this study was to evaluate the disinfection of dentinal tubules with diclofenac sodium (DS), N-acetylcysteine (NAC) and calcium hydroxide (CH). Contaminated dentinal blocks were divided into two control and seven experimental groups (n = 15): CH, DS, NAC, CH + 5% DS, 50% CH + 50% DS, CH + 5% NAC and 50% CH + 50% NAC. After seven days, dentine debris was obtained from two depths of 100 and 200 µm.

Relative frequency of hepatitis B virus, human papilloma virus, Epstein-Barr virus, and herpes simplex viruses in the semen of fertile and infertile men in Shiraz, Iran: A cross-sectional study.

Background: About 8-12% of couples on reproductive age suffers from infertility worldwide. Since 1993, the role of genital tract infections by microbes, including viruses that can infect the sperm, in human infertility has been proposed.

Objective: To investigate the frequency of hepatitis B virus (HBV), human papilloma virus (HPV), Epstein-Barr virus (EBV), and herpes simplex virus (HSV) infection in the semen of fertile and infertile men referred to the Mother and Child Hospital, Shiraz, Iran.

SARS-CoV-2 effects on male reproduction: should men be worried??

The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has placed a global challenge on both healthcare and society. So far, studies have shown that men are more prone to become ill than women and are more likely to die compared to female patients. Higher rates of positive cases and fatality in men than women have drawn the attention of scientists to investigate the possible impacts of SARS-CoV-2 on the male reproductive system.

Surface roughness, plaque accumulation, and cytotoxicity of provisional restorative materials fabricated by different methods.

Fabricating method may affect the surface properties and biological characteristics of provisional restorations. This study aimed to evaluate the surface roughness, plaque accumulation, and cytotoxicity of provisional restorative materials fabricated by the conventional, digital subtractive and additive methods. Sixty-six bar-shaped specimens (2×4×10 mm) were fabricated by using provisional restorative materials through the conventional, digital subtractive and additive methods (n = 22 per group).

Evaluation of the Preventive Effect of Composites Containing Silver and TiO Nanoparticles on Demineralization around Orthodontic Brackets.

Aim: The aim of this study was to investigate the antidemineralization effect of composites containing silver and titanium dioxide (TiO) nanoparticles used for bonding brackets to tooth specimens.

Materials And Methods: A total of 75 freshly extracted teeth were etched and primed and then randomly assigned to three adhesive groups: (1) conventional orthodontic adhesive, (2) conventional adhesive mixed with TiO nanoparticles, and (3) conventional adhesive mixed with silver nanoparticles. In each group, brackets were bonded with the pertinent adhesive.

Characterization and antibiotic resistance pattern of diffusely adherent (DAEC), isolated from paediatric diarrhoea in Shiraz, southern Iran.

Diarrhoea is a major health concern, especially in developing countries. Research has implicated diffusely adherent (DAEC) strains as a cause of diarrhoea. In this study, we investigated the prevalence, adherence assay, virulence gene profiles and antimicrobial resistance of DAEC at a hospital in southern Iran.

Photodynamic antimicrobial chemotherapy using indocyanine green in experimentally induced intraoral ulcers in rats.

Background: Photodynamic antimicrobial chemotherapy (PACT) is a promising modality for eradication of microorganisms from the wound. This study aimed to investigate the effectiveness of PACT using indocyanine green (ICG) for reduction of bacterial load of oral ulcers in rats and its impact on the healing process.

Methods: In this experimental study, 50 adult male Sprague Dawley rats were recruited.

The first report of carrying in Iran.

Objectives: Prompt detection of extended-spectrum β-lactamases (ESBL) and carbapenemase-producing enterobacteriaceae is crucial for infection prevention and control strategies. The present study aimed to characterize the ESBL and carbapenemase genes among isolates from an Iranian inpatient population.

Materials And Methods: A total of 96 isolates obtained from inpatients between June 2016 and March 2017, were identified by the conventional microbiological methods and diagnostic kits.

Bacterial infection of the male reproductive system causing infertility.

Bacterial infections play a disruptive and hidden role in male reproductive failure. Different kinds of bacteria are often able to interfere with reproductive function in both sexes and lead to infertility. In this study, to further evaluate the role of bacterial infections in male reproduction we provided an extensive overview of so far researches investigating the effects of bacterial infections on male fertility.