Publications by authors named "Motamarri Venkata Naga Lalitha Chaitanya"
Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disorder (ND), affecting more than 44 million individuals globally as of 2023. It is characterized by cognitive dysfunction and an inability to perform daily activities. The progression of AD is associated with the accumulation of amyloid beta (Aβ), the formation of neurofibrillary tangles (NFT), increased oxidative stress, neuroinflammation, mitochondrial dysfunction, and endoplasmic reticulum stress.
View Article and Find Full Text PDFReconciling the Gap between Medications and their Potential Leads: The Role of Marine Metabolites in the Discovery of New Anticancer Drugs: A Comprehensive Review.
Janvee Thaman Rashmi Saxena Pal Motamarri Venkata Naga Lalitha Chaitanya Palakurthi Yanadaiah Prabha Thangavelu
Curr Pharm Des
January 2024
Article Synopsis
- * Advancements in genomic and bioinformatics research have enhanced our understanding of the complex genetic interactions that contribute to cancer, but challenges like epigenetic resistance remain obstacles in effective treatment development.
- * Although many anticancer drugs stem from natural sources, particularly plants and microorganisms, there is a notable gap in research on algae-based treatments, prompting a review of their potential as innovative therapeutic options.
Rosmarinic acid (RA) is a polyphenolic metabolite found in various culinary, dietary sources, and medicinal plants like (Linn) Benth., Linn., Linn.
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