Participation of immune complexes in adenovirus infection.

To determine the participation of immune complexes during adenovirus infection, we evaluated serum and necropsy specimens of patients with confirmed adenovirus infection of the lower respiratory tract. In lung and kidney from seven dead patients, immunofluorescence revealed the presence of hexon, immunoglobulins and complement. These patients had clinical manifestations of kidney dysfunction.

[Hypertensive reaction to exercise. Retrospective studies of 1363 consecutive exercise tests].

Objective: To study exercise hypertensive reaction and its relation with rest blood pressure, hypertension type and hypertensive cardiac disease.

Design: Retrospective study of treadmill exercise testes (ET) performed from January/89 to June/91: (n: 1703).

Setting: Stress tests Laboratory of Cardiology Service of a Military Hospital.

A case-control study on the association of hepatitis B virus infection and hepatocellular carcinoma in northeast Brazil.

Hepatitis B virus (HBV) serological markers were investigated in 40 incident cases of hepatocellular carcinoma (HCC) and in two age and sex matched control groups, comprising 40 patients with other cancers and 80 healthy individuals, resident in Bahia, Brazil. Serologic tests were done by radioimmunoassay. The study observed high proportion of seropositivity to HBsAg (42.

[Ibopamine in the treatment of congestive heart failure. Multicenter follow-up study].

Objective: To assess safety and efficacy of ibopamine, 200 mg TID, added to conventional treatment of congestive heart failure.

Design: A prospective, longterm, open study over two years (1986-88). A multicenter trial.

[The assessment of parasitemia in women who are carriers of Trypanosoma cruzi infection during and after pregnancy].

This paper presents an evaluation of the parasitemic profiles of 119 women chronically infected with T. cruzi. Xenodiagnosis (xenos) were applied during (465 xenos) and after pregnancy (363 xenos) in order to detect possible variations in parasitemia in these periods.

Antegrade and retrograde cardioplegia with different reperfusion techniques in patients with multiple coronary artery lesions.

To evaluate the effectiveness of retrograde cardioplegia and reperfusion, a total of 266 patients undergoing coronary bypass surgery between Nov 1987 to Dec 1989 were divided into three groups depending on the method of cardioplegic fluid delivery and reperfusion. In group I (80 patients) antegrade cardioplegia and reperfusion was used. In group II (98 patients) antegrade and retrograde cardioplegia and antegrade reperfusion was used while in group III antegrade and retrograde cardioplegia and retrograde reperfusion was used.

[Congenital cardiopathies at an internal medicine service].

Study Objective: Description of 32 cases of congenital heart disease in the adulthood, admitted in the First Department of Medicine of Hospital Santa Maria, Lisboa between 1980 and 1989.

Design: Retrospective study.

Setting: Admission from the Emergency Room and Outpatients Clinic to an Internal Medicine Department of a General Hospital.

[Pressure response to dynamic exercise and antihypertensive therapy].

Objectives: To study the exercise systolic pressure (SP) in hypertensive patients, its relation with left ventricular (LV) mass and the efficacy of its control by some antihypertensive drugs.

Design: To study the echocardiogram (ECHO) and exercise test (ET) in hypertensives (HT), before and after rest blood pressure (BP) control.

Setting: Out-patient cardiology clinic in a military hospital.

[Protective effect of intradermal BCG on tuberculous meningitis].

The incidence of tuberculosis in Bahia, though declining, remains very high, and one of the severe forms of the disease is tubercular meningitis. This case-control study sought to compare confirmed cases of tubercular meningitis in children 0 to 14 years of age with members of a control group, matched as closely as possible for age (not more than about six months apart), who had shown no sign of meningitis or neurological disease. The comparison considered such factors as schooling of the parents, their occupations, exposure to the bacillus at home, and others.

[The patient with acute cerebrovascular disorders: assessment of associated diseases].

We performed a prospective study in 106 patients with acute stroke. The main purpose was to evaluate the associated diseases and to determine their prevalence and incidence in two different types of cerebrovascular disease: the intracerebral hemorrhage (HI) and ischaemic events (AI). The studied population included 54 men and 52 women with a mean age of 66.

[The effectiveness of amiodarone seems to depend highly on the pathology underlying the arrhythmia].

Study Objective: To evaluate the efficacy of amiodarone in tachyarrhythmias occurring acutely, in patients with different nosological entities of the heart.

Design: A retrospective study.

Setting: Emergency-room patients and ward-patients, in an Internal Medicine Department of a University Hospital.

[The importance of heart disease in the various types of cerebral vascular disease. A prospective study].

Unlabelled: A prospective study was performed in 106 patients with acute stroke. The main purpose was the cardiac evaluation in the different types of cerebrovascular disease: Intracerebral hemorrhage (H), Cortical ischaemic events (C) and Subcortical ischaemic events (SC) and also to evaluate the interest of echocardiography in detecting occult cardiac sources of emboli. The study population included 54 men and 52 women with a mean age of 66.

A nine year prospective study of Chagas' disease in a defined rural population in northeast Brazil.

The association between infection with Trypanosoma cruzi and the development of electrocardiographic alterations and mortality was studied longitudinally for 9 years in a population residing in an endemic area in Castro Alves, Bahia, Brazil. Annual censuses were begun in 1973. At 3 year intervals from 1974 to 1983, the population was examined serologically and subjected to electrocardiography using standardized techniques.

[Hyponatremia--new concepts and therapy. Apropos of a clinical case].

The therapeutic approach of hyponatremia is reviewed, and the authors describe their recent experience of a clinical case of a woman with acute hyponatremia. After analysing the main publications of the last years, they conclude that the way of correcting hyponatremia largely depends of its acute or chronic character. Chronic hyponatremia must be corrected with slow rate infusion of sodium chloride (0.

[Cerebral vascular disorders and arterial hypertension: cardiologic and neurologic aspects].

Objective: To report and discuss some cardiologic, neurologic and radiologic aspects in different types of stroke (AVC) present in hypertensive patients.

Design: Retrospective study in patients with acute cerebrovascular accident (AVC) and high blood pressure (HTA). Separate this population in three groups according to the results of computerized tomography scanning of the brain (TAC): hemorrhage (H) cerebral infarction (IC) and lacune (L).

Independent evolution of structural and coding regions in a Neurospora mitochondrial intron.

The discovery of intervening sequences (introns) in eukaryotic genes has raised questions about the origin and evolution of these sequences. Hypotheses concerning these topics usually consider the intron as a unit that could be lost or gained over time, or as a region within which recombination can occur to facilitate the production of new proteins by exon shuffling. Additional complexities are observed in introns of mitochondrial and chloroplast genes which contain secondary structures required for messenger RNA splicing and open-reading frames encoding proteins.

Fluid balance and the adult respiratory distress syndrome.

This study examined the effect of fluid balance on survival in ARDS. Of the 213 patients entered into a prospective data collection study, we evaluated 113 patients who met strict criteria for ARDS. Multiple variables were analyzed for as long as 14 days after intubation including cardiac output, pulmonary capillary wedge pressure, mean blood pressure, intake minus output (I-O), cumulative intake minus output (cum I-O), and change in weight (delta wt).