Assessment of the Number of Missing Tooth Surfaces and the Molecular Findings on the Outcomes of Vital Pulp Therapy Using Two Calcium Silicate Materials: A Randomized Clinical Study.

Introduction: This study aimed to evaluate the clinical and radiographic outcomes of full pulpotomy in mandibular molar teeth with symptomatic irreversible pulpitis. It compared class I and class II cavity defects and correlated these outcomes with the quantification of two biomolecules (TNF-α and MMP-9) using two types of pulpotomy dressing materials (MTA+ and Well-Root PT).

Methodology: Sixty patients were selected and categorized based on cavity class.