Publications by authors named "Mostafa Kamandi"
Article Synopsis
- The study aimed to evaluate serum markers, specifically Pro BNP, for diagnosing and predicting outcomes in acute heart diseases within emergency settings.
- Conducted with 100 patients experiencing syncope, the findings revealed that 19% had cardiac syncope, and Pro BNP levels were significantly higher in those with cardiac issues and ECG abnormalities.
- The research concluded that elevated Pro BNP levels correlated with age and hospitalization duration, indicating its strong potential as a diagnostic tool for cardiac syncope, with high sensitivity (94.73%) but lower specificity (56.79%).
The evaluation of atorvastatin as an adjunct to fluconazole for the anti-fungal prophylaxis in acute myeloid leukemia: a multicenter, triple-blinded, randomized clinical trial.
Naunyn Schmiedebergs Arch Pharmacol
June 2024
Article Synopsis
- * Conducted among 76 AML patients in a multicenter, triple-blind setup, the research found that atorvastatin significantly reduced the incidence of IFIs compared to a placebo, leading to better IFI-free survival rates.
- * No severe side effects from atorvastatin were reported, supporting previous findings about the antifungal properties of statins and highlighting the need for further research with larger groups and longer follow-ups.
Background And Aims: The effect of stopping or reducing the dose of vincristine in diffuse large B-cell lymphoma (DLBCL) on the outcome and prognosis of the disease is still in doubt. The present study aimed to investigate and compare the prognosis and complete remission of two R-CHOP treatment regimens with and without vincristine reduction in DLBCL patients.
Methods: This retrospective study was conducted on newly diagnosed DLBCL patients during 2018-2021.
Introduction: Several A number of prognostic blood markers related tofor Diffuse Large B-Cell Lymphoma (DLBCL) have been identified, most of which are costly and not easily availableaccessible. Although the relationship between the prognostic role of RDW and some cancers has been well established, the role it of RDW plays in DLBCL patients is unclear still questionable and requires more investigations.
Methods: All patients diagnosed with DLBCL who had referred to Imam Reza Hospital, during were included in this retrospective cohort study.
Background: Mild head trauma often causes several complications and disabilities including nausea and vomiting in hospitalized people. The aim of the present study was to compare the effectiveness of metoclopramide and ondansetron, and compare it with placebo to control nausea in the patients with mild head trauma admitted to the emergency department.
Methods: This is a randomized double-blind placebo-controlled clinical trial conducted on the patients with mild head trauma and normal brain CT scans who were admitted to the emergency department within 24 hours after the injury.
Article Synopsis
- Vaccination has proven to be a key method in controlling the COVID-19 pandemic, prompting a meta-analysis to assess the effectiveness of various COVID-19 vaccines in reducing infection, hospitalization, and mortality rates.
- The study reviewed 54 different research articles and found that the effectiveness of COVID-19 vaccines significantly increased after the second dose, with Pooled Vaccine Effectiveness (PVE) reaching 87% for infections and 89% for hospitalizations.
- The analysis concluded that vaccines BNT162b2 mRNA, mRNA-1273, and ChAdOx1 demonstrated high effectiveness in preventing COVID-19-related issues, suggesting their continued use for disease prevention.
Since SARS-CoV-2 infection is rapidly spreading all around the world, affecting many people and exhausting health care resources, therapeutic options must be quickly investigated in order to develop a safe and effective treatment. The present study was designed to evaluate the safety and efficacy of convalescent plasma (CP) for treating severe cases of COVID-19 who developed acute respiratory distress syndrome (ARDS). Among 64 confirmed cases of severe COVID-19 with ARDS in this study, 32 patients received CP besides first line treatment.
View Article and Find Full Text PDFPurpose: Acute macular neuroretinopathy (AMN) is a visual-deteriorating rare clinical entity with an uncertain etiology. We aimed to report a case of AMN and underlying disease of acute myeloid leukemia (AML).
Case Presentation: A thirty-five-year-old female patient with bone marrow biopsy confirmed AML, and bicytopenia, under chemotherapy, complained of sudden paracentral visual field defect in her right eye was referred.
Objectives: In this study, we investigate the effect of hydroxychloroquine on the prevention of Novel Coronavirus Disease (COVID-19) in cancer patients being treated.
Trial Design: This is a multi-centre, two-arm, parallel-group, triple-blind, phase 2-3 randomised controlled trial.
Participants: All patients over the age of 15 from 5 types of cancer are included in the study.
Given the probable role of JC virus in associate with increasing the odds of colorectal cancer, this study was conducted systematically to evaluate the association between JC virus and colorectal cancer. Systematic reviews of the articles published prior to January 1, 2019 without time and place limitations were done independently through the PubMed, ISI, EMBASE and Medline main databases. The heterogeneity rate was assessed through I2, Chi2 and Tau2, and the sensitivity analysis and meta-regression were used to investigate the source of heterogeneity among the studies.
View Article and Find Full Text PDFObjectives: Since poisoning is one of the most important preventable factors contributing to the hospitalization and death of children who present to emergency departments, this study was carried out to investigate the risk factors contributing to the incidence and mortality of acute childhood poisoning.
Methods: This hospital-based case-control study included 243 cases and 489 controls, drawn from daily admissions to the emergency departments of the included hospitals according to the inclusion and exclusion criteria.
Results: Gastrointestinal poisoning was the most common poisoning type, found in 87.