Publications by authors named "Mostafa Elkhiary"
Article Synopsis
- Gene therapy using a targeted adenovirus vector (Ad-SSTR-RGD-TK/GCV) shows promise for treating uterine leiomyoma by selectively inducing cell death in tumor cells while leaving normal cells unharmed.
- An in-vivo study in mice demonstrated that the targeted vector significantly shrank tumor size, reduced cancer cell proliferation markers, and induced apoptosis compared to untargeted vectors, with no spread of the virus to other tissues.
- The findings suggest that this targeted gene therapy approach could be a safe and effective method for treating leiomyoma, warranting further research in preclinical models before human trials.
To describe and evaluate the safety and feasibility of a new clampless technique using aneurysm needle for vaginal hysterectomy compared with the standard technique as a less minimally-invasive procedure in women with benign large volume non-prolapse uteri.Study design In a pilot study, series of 46 consecutive women with benign large volume (200-500cm(3)) uterine conditions other than pelvic organ prolapse were planned for vaginal hysterectomy (VH). Patients were divided into 2 groups; group-A (21 women): for whom an (aneurysm needle clampless VH) was performed; group-B (25 women): used as a control (standard VH).
View Article and Find Full Text PDFBackground: Gestational gigantomastia is a nightmare to pregnant women. The currently available surgical intervention is either reduction mammoplasty or simple mastectomy. Reduction mammoplasty carries high risk of recurrence.
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