Publications by authors named "Mostafa E Metawee"
Article Synopsis
- Melatonin (MTN) is a neuro-hormone from the pineal gland that regulates sleep and has protective effects in neurodegenerative diseases like Parkinson's disease (PD), where its levels are significantly reduced.
- The review discusses various reasons for low MTN in PD, such as reduced light exposure, issues with retinal light transmission, SCN degeneration, and dysautonomia, leading to issues like excessive daytime sleepiness.
- The study suggests that the decline in MTN levels relates to the severity of PD and highlights the need for further research to understand the mechanisms behind this dysregulation and potential use of MTN as a biomarker for PD.
Background: Hemolytic anemia (HA) is a serious health condition resulting from reduced erythrocytes' average life span. Echinochrome (Ech) is a dark-red pigment found in shells and spines of sea urchins.
Aim: Studying the potential therapeutic effect of Ech on phenylhydrazine (PHZ)-induced HA in rats.
Combined Methylprednisolone Pulse Therapy plus Rituximab for Treating a Rare Juvenile Steroid-Resistant Nephrotic Syndrome with Cerebral Venous Sinus Thrombosis: A Case Report.
J Cardiovasc Dev Dis
November 2022
: Cerebral venous sinus thrombosis (CVST) secondary to nephrotic syndrome (NS) is rarely reported. Additionally, treating steroid-sensitive nephrotic syndrome (SSNS) that changes to steroid resistance (SRNS) is difficult, with many relapses and side effects. : A 32-month-old SSNS male child turned into SRNS and developed cerebral venous sinus thrombosis (CVST), a rare complication of NS.
View Article and Find Full Text PDFDiabetes mellitus is an oxidative stress-related disease characterized by hyperglycemia and a variety of complications, including nephropathy. Vitamin D has variable functions extending beyond the calcium metabolism to prevent oxidative tissue damage. We aimed to investigate whether vitamin D supplements could enhance Glibenclamide's effectiveness in treating diabetes and minimize the risk of associated pathology.
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