Mitochondrial DNA Copy Number, a Damage-Associated Molecular Pattern Molecule, Can Predict Pancreatic Necrosis and Is Correlated with the Severity of Acute Pancreatitis.

Background: Mitochondrial DNA (mtDNA) is a damage-associated molecular pattern molecule that can trigger an immune-inflammatory response during pancreatic necrosis (PN).

Aim: To evaluate the role of mtDNA in the detection of PN and severe acute pancreatitis (SAP).

Methods: The present study included 40 AP patients and 30 controls.