Treatment of coronary bifurcation lesions with drug-eluting stents: insights from the first phase of the prospective multicenter german drug-eluting stent registry.

Background: Controversy exists about the impact of treating bifurcations on overall outcome of coronary interventions using drug-eluting stents (DES). We sought to investigate 1-year outcome of the treatment of bifurcation lesions using DES in a large "real-world" cohort.

Methods And Results: Among 5,126 patients enrolled in phase I of the multicenter German Drug-Eluting Stent Registry, 814 (16%) were treated for a bifurcation lesion.

Spatial distribution and temporal trends of persistent organochlorine pollutants in sediments from Lake Maryut, Alexandria, Egypt.

Organochlorine compounds (OCs) in surface and core sediments collected from Lake Maryut, Egypt, were examined to elucidate their distribution, ecological risk and historical trend. To our knowledge, this is the first study on residue levels of OCs in sediments from Lake Maryut. Concentrations of PCBs and DDTs were higher than other OCs, ranging from 3.

Host plant suitability and feeding preferences of the grapevine pest Abagrotis orbis (Lepidoptera: Noctuidae).

Thirteen plant species were tested for their suitability as hosts for Abagrotis orbis (Grote), a climbing cutworm pest of grapevines in British Columbia. Choice tests were also conducted to investigate larval feeding preferences for the Brassicaceae species joi choi, Brassica rapa variety. Chinensis L.

Radiographic evaluation of early periprosthetic femoral bone contrast and prosthetic stem alignment after uncemented and cemented total hip replacement in dogs.

Objective: To radiographically evaluate periprosthetic femoral bone contrast and assess alignment of the prosthetic stem after uncemented and cemented total hip replacement (THR).

Study Design: Prospective clinical study.

Animals: Dogs (n = 15).

Continuing threat of influenza (H5N1) virus circulation in Egypt.

Reservoirs for the continuing influenza (H5N1) outbreaks in Egypt are ill-defined. Through active surveillance, we detected highly pathogenic influenza subtype H5 viruses in all poultry sectors; incidence was 5%. No other subtypes were found.

Induction of Biologically Active Flavonoids in Cell Cultures of Morus nigra and Testing their Hypoglycemic Efficacy.

The antidiabetic activity of both leaves and MJ-treated cell cultures of Morus nigra was evaluated after their oral administration to streptozotocin-induced diabetic rats. The antidiabetic activity of extracts from leaves given to streptozotocin (STZ)-diabetic rats for 10 days increased with increasing doses of leaves extract up to 500 mg/kg/day. The administration of 500 mg/kg/day of leaves extract reduced the concentration of glucose from 370 ± 7.

Comparison of outcomes in patients having isolated transcatheter aortic valve implantation versus combined with preprocedural percutaneous coronary intervention.

Coronary artery disease negatively affects the outcome of patients undergoing surgical aortic valve replacement and practice guidelines recommend revascularization at time of surgery. In patients undergoing transcatheter aortic valve implantation (TAVI), the impact of preprocedural percutaneous coronary intervention (PCI) on TAVI outcome has not been examined. We aimed in the present study to assess the feasibility and safety of performing PCI before TAVI and to evaluate procedural, 30-day, and 6-month clinical outcomes.

Laparoscopic management of primary pelvi-ureteric junction obstruction: Single-centre experience.

Objective: To evaluate the effect and safety of laparoscopic pyeloplasty in the treatment of pelvi-ureteric junction obstruction (PUJO).

Patients And Methods: In 34 patients, laparoscopic dismembered pyeloplasty was used to treat primary PUJO. Information was obtained for symptoms, results of a nuclear scan before and after surgery, intraoperative blood loss, operative duration, stenting method, and hospital stay.

A survey of selected essential and heavy metals in milk from different regions of Egypt using ICP-AES.

The aim of this paper was to assess the content of selected essential metals (Fe, Zn, Cu and Cr) and some heavy metals (Pb and Cd) in raw cow's milk collected from different Egyptian areas during different periods of one year (January-February, May-June and September-October 2009). Twenty-one samples of raw milk were analysed using inductively coupled plasma-atomic emission spectrometry for quantitative determination. The highest metal accumulation levels for Cd, Cr, Fe and Cu are found in milk samples collected from Shubra, while samples from Menofia and Tanash are high in Pb and Zn, respectively.

Chemical characterization of some substituted hydroxyapatites.

Synthetic multi-substituted hydroxyapatite nano powders containing silicon and or carbonate prepared by a wet chemical method. The process parameters are set up to allow the simultaneous substitution of carbonate and silicon ions in the place of phosphorus. The chemical and structural characterizations of the prepared powders are determined with the aid of; XRF, ICP, XRD and FTIR.

Parotidectomy for benign parotid tumors: an aesthetic approach.

Background/aims: The sternocleidomastoid (SCM) partial thickness muscle flap is among the various methods described to correct parotidectomy defects, but its indications and limitations are not clearly demonstrated in several reports. This study was done to test the aesthetic outcome of this method, its indications and limitations. The technique was combined with a face lift incision to further improve the outcome.

Distribution of axillary lymph node metastases in different levels and groups in breast cancer, a pathological study.

Background: It was observed during dissection of heavy deposits of axillary lymph nodes (LNs) in breast cancer that there were grossly positive LNs outside the confines of classical axillary dissection.

Aim Of Study: To know the extent of LN metastases in these new basins by dissecting and labeling them separately, for pathological examination and proper staging of those patients.

Patients And Methods: From 2005 to 2009, 59 private patients with breast cancer who had positive axillary LNs were subjected to axillary dissection with accurate leveling according to its relation to pectoralis minor.

Investigation of the volatile composition of pinotage wines fermented with different malolactic starter cultures using comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC-TOF-MS).

Headspace solid phase microextraction in combination with comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (HS-SPME-GC × GC-TOF-MS) was used for the detailed investigation of the impact of malolactic fermentation (MLF) using three commercial Oenococcus oeni strains on the volatile composition of Vitis vinifera cv. Pinotage wines. GC × GC allowed the identification of 115 volatile compounds, including both major constituents and trace-level compounds, in a single analysis.

Influence of mutation of the HFE gene on the progression of chronic viral hepatitis B and C in Moroccan patients.

The implication of hemochromatosis (HFE) gene mutations in chronic viral hepatitis remains controversial. The aim of the present study was to measure the frequencies of the common HFE gene mutations in Moroccan subjects with chronic viral hepatitis B and C and to assess their influence on the progression of liver disease. H63D and C282Y mutations were screened by the polymerase chain reaction followed by restriction fragment length polymorphism analysis in 170 chronic hepatitis B patients, 168 chronic hepatitis C patients, and 200 healthy controls.

Preemptive peritonsillar ketamine infiltration: postoperative analgesic efficacy versus meperidine.

Objectives: The current study was planned to assess post-tonsillectomy analgesic efficacy of pre-emptive peritonsillar ketamine infiltration with or without bupivacaine in comparison to meperidine alone or in combination with bupivacaine.

Patients & Methods: The study included 100 patients with mean age of 10.5 +/- 2.

Risk posed by chlorinated organic compounds in Abu Qir Bay, East Alexandria, Egypt.

Introduction: In Egypt, the picture of threats to humans and the environment from the exposure to organic pollutants is still incomplete. Thus the objectives of this study were to assess the occurrence and distribution of polychlorinated biphenyls (PCBs), organochlorine pesticides, and chlorpyrifos in sediments and mussels of Abu Qir Bay and their risks for environment and human health.

Materials And Methods: Twenty-three different compounds organochlorines were determined in 20 surfacial sediment and 10 mussel samples by gas chromatography-electron capture detector.

Prospective multi-centre study of adjustable single-incision mini-sling (Ajust(®) ) in the management of stress urinary incontinence in women: 1-year follow-up study.

Objectives: To determine whether an adjustable single-incision mini-sling (SIMS, Ajust(®) ) is safe and effective in the management of female stress urinary incontinence (SUI) at 12 months follow-up. To determine whether it is feasible to be performed under local anesthesia (LA).

Materials And Methods: The present study is a multicentre prospective cohort study in which 90 female patients underwent SIMS-Ajust(®) using a standardized insertion technique.

Preoperative urodynamic predictors of short-term voiding dysfunction following a transobturator tension-free vaginal tape procedure.

Objective: To determine whether preoperative urodynamic parameters can predict the development of short-term voiding dysfunction (VD) after a transobturator tension-free vaginal tape (TO-TVT) procedure.

Methods: In a prospective study between April 2005 and April 2007, 341 women were randomized to receive "inside-out" or "outside-in" TO-TVT. The present secondary analysis included women who had completed a preoperative symptom questionnaire, had a voided volume of 100mL or more on preoperative uroflowmetry, and underwent standardized postoperative voiding assessment.

Cinnamon extract ameliorates ionizing radiation-induced cellular injury in rats.

The present study aimed to investigate the protective role of cinnamon extract against inflammatory and oxidative injuries in gamma irradiated rats. Rats were subjected to fractionated doses of gamma radiation. Cinnamon extract were daily administrated before starting irradiation and continued after radiation exposure.

Distribution and characteristics of PAHs in sediments from the Mediterranean coastal environment of Egypt.

To assess the contamination of polycyclic aromatic hydrocarbons (PAHs) in the Mediterranean coastal environment of Egypt, 26 sediment samples from the coastline, harbours, estuaries and coastal lakes were collected and analyzed. The sediment PAH concentrations of thirty-nine 2-6 ring PAHs ranged from 13.5 to 22,600 ng/g.

A comprehensive introduction to the genetic basis of non-syndromic hearing loss in the Saudi Arabian population.

Background: Hearing loss is a clinically and genetically heterogeneous disorder. Mutations in the DFNB1 locus have been reported to be the most common cause of autosomal recessive non-syndromic hearing loss worldwide. Apart from DFNB1, many other loci and their underlying genes have also been identified and the basis of our study was to provide a comprehensive introduction to the delineation of the molecular basis of non-syndromic hearing loss in the Saudi Arabian population.

Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry.

Carbofuran (CFN), carbosulfan (CSN) and fenobucarb (FBC) are carbamate pesticides that are widely used in gardening and agriculture for the control of insects. Human poisoning due to occupational or self-poisoning exposures is also reported, so assays are required to quantify the plasma concentration of these insecticides. An LC-MS/MS method was developed and validated for the simultaneous quantification of these three carbamate insecticides in the plasma of patients with acute intentional self-poisoning.

Synthesis and spectroscopic studies on charge-transfer molecular complexes formed in the reaction of imidazole and 1-benzylimidazole with σ- and π-acceptors.

The spectrophotometric characteristics of the solid charge-transfer molecular complexes (CT) formed in the reaction of the electron donors imidazole (IML) and 1-benzylimidazole (BIML) with the σ-acceptor iodine and π-acceptors 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), tetracyanoethylene (TCNE) and 2,3,5,6-tetrachloro-1,4-benzoquinone (CHL) have been studied in chloroform at 25 °C. These were investigated through electronic and infrared spectra as well as elemental analysis. The results show that the formed solid CT-complexes have the formulas [(IML)2 I]I3, [(IML)(DDQ)], [(IML)2(TCNE)5] and [(IML)(CHL)] for imidazole and [(BIML) I]I3, [(BIML)(DDQ)2], [(BIML)(TCNE)2] and [(BIML)(CHL)2] for 1-benzylimidazole in full agreement with the known reaction stoichiometries in solution as well as the elemental measurements.

The interplay of YKL-40 and leptin in type 2 diabetic obese patients.

Recently, YKL-40 has been identified as a new inflammatory marker of type 2 diabetes mellitus (T2DM), while leptin is one of the most important adipose derived hormones. However, the relationship between them has not been elucidated. Therefore this study aimed to study their correlation in obese T2DM patients.