A brief literature review of low-level laser therapy for treating amyotrophic lateral sclerosis and confirmation of its effectiveness.

Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a steadily progressive course due to the death of central and peripheral motor neurons responsible for voluntary movements. Low-level laser therapy (LLLT) is a treatment method unique in its universality and efficacy, particularly for neurodegenerative diseases.

Methods: In this review, we discuss the effect and application of LLLT in the treatment of ALS.

[Low-level laser therapy in oncology - what's new? Analysis of 2018-2021 publications].

Unlabelled: Low-level laser therapy (LLLT) is included in the Federal project «Fight against oncological diseases», which provides for equipping all specialized medical institutions in Russia with the appropriate devices until 2026.

Purpose Of The Study: Publications analysis on the use of LLLT in oncology.

Material And Methods: To search for publications, databases and libraries were used: PubMed, Scopus, ResearchGate, Google Scholar, J-STAGE, eLibrary.

[Optimizing laser therapy parameters in pharyngeal tonsil diseases in children].

Unlabelled: In children, chronic inflammatory diseases of the pharyngeal lymphoid ring are the most common chronic nasopharyngeal diseases. Available therapies are not always effective, associated with an increase in treatment duration and possible complications and recurrences. Laser therapy (LT) techniques have long been successfully used in ENT practice, but they still need to be optimized and standardized.

[Laser therapy effect on endothelial dysfunction in patients after the surgery for orthognathic disorders].

Objective: To optimize postoperative rehabilitation by applying low-intensity laser irradiation (LILI) with different wavelengths in the early postoperative period to prevent inflammatory complications.

Material And Methods: After radiological examination and ultrasound diagnostics of the periodontal tissue vessels, surgical methods of orthognathic treatment were performed, after completion of which a course of LILI was carried out. The VEGF its receptors (sVEGF-R1; sVEGF-R2) content was measured by enzyme immunoassay using standard reagent kits.

Low-Level Laser Therapy for Herpesvirus Infections: A Narrative Literature Review.

Herpesvirus infection has a variety of clinical forms and is extremely widespread in the world while existing treatment methods are not always quite effective. The search for new treatment modalities is a relevant problem and numerous studies show the therapeutic effect of low-level laser therapy (LLLT) on different herpesvirus types. The mechanisms of laser light action and the impact of LLLT on the pathological pathways of herpes infections are described.

Methods of effective low-level laser therapy in the treatment of patients with bronchial asthma (literature review).

Bronchial asthma is an autoimmune disease, one of the most common and practically non-treatable by standard methods. At present, the used drugs only maintain a state of temporary remission, simultaneously having a negative effect on various organs and structures and causing side effects. At the same time, the experts have ignored more than 50 years of successful experience of low-level laser therapy, the results of hundreds of studies proving the effectiveness of the method in treating patients with all forms of bronchial asthma.

Low-Level Laser Therapy in Prevention of the Development of Endothelial Dysfunction and Clinical Experience of Treatment and Rehabilitation of COVID-19 Patients.

Objectives: The aim of the article is to justify the application of low-level laser therapy (LLLT) to prevent the development of endothelial dysfunction in COVID-19 patients. The results of treating and rehabilitating patients with COVID-19 and prevention of the disease using low-level laser therapy (LLLT) are evaluated.

Methods: A literature review is conducted on mechanisms of vascular homeostasis regulation, biomodulating effect of laser light, and LLLT methods for preventing endothelial dysfunction.

LASMIK laser biorevitalization: mechanisms and therapeutic experience.

LASMIK laser biorevitalization is a well-known technology developed in Russia that is based on laser phoresis as a method to enhance percutaneous penetration of substances. The article describes the mechanisms that act here and factors that determine the optimal parameters of the technique. The research conducted for 2 years allowed to optimize the parameters of the laser phoresis technique, testing the LASMIK laser biorevitalization technology.

Laser Acupuncture: 35 Years of Successful Application in Russia (Narrative Review).

Laser acupuncture is one of the low-level laser therapy (LLLT) methods, replacing the traditional technique of Chinese needle acupuncture. This article describes the main principles and parameters of laser acupuncture based on the analysis of 35 years of successful experience in applying the method in Russia. The search of the literature on laser acupuncture was made in the Russian Medical Library and the Russian State Library (1498 publications in Russian), and PubMed/Medline (117 publications in English).

The Use of Laser Therapy for Patients with Fibromyalgia: A Critical Literary Review.

The management of pain - despite many anaesthetic drugs - remains to be an urgent task. If the goal is to achieve permanent pain relief - and not to temporarily mask the pain (masking pathology) - then this goal can only be achieved by treating pain with physiotherapeutic methods, the most universal and effective of which, is low level laser therapy (LLLT). The treatment methods vary fundamentally in the case of neuropathic (nonspecific, primary) pain, which includes pain with the localization of the trigger points (TP) and nociceptive (specific, secondary), which includes all types of pain resulting from trauma, inflammation, etc.

A brief literature review and own clinical experience in prophylaxis of oral mucositis in children using low level laser therapy.

Objective: The article describes the experience of clinical application of low level laser therapy in pediatric oncology for the prevention and treatment of chemotherapy complications such as oral mucositis.

Background: For this purpose, for the first time in the world non-invasive laser blood illumination is used on the sinocarotid zone (on the projection of the common carotid artery symmetrically) and popliteal fossa in order to stimulate the phagocytic activity of leukocytes.

Methods: 25 children with different oncological diseases were given non-invasive laser blood illumination treatment (904 nm, pulse mode, 100 ns, 50-150 Hz, 5-7 W, 4 cm, 1-2 minutes daily per each procedure) 1-3 days before the beginning of chemotherapy.

[Transcranial electrostimulation and serotonin laser phoresis in the athletes experiencing a combined effect of fatigue and psycho-emotional stress].

Rationale: At sports submaximal loads accompanied by muscle fatigue due to metabolic transformations, the conditions are created for the development of combined endogenous and exogenous emotional stresses. An important role in the development of stress is played by the state of adaptation mechanisms, in which sintoxic and catatoxic programs are involved, as well as the GABA-dopaminergic system. There is insufficient information on the possibilities for reducing the manifestations of stress.

[The application of combined low-intensity laser therapy for the treatment of the patients presenting with trophic ulcers associated with chronic venous insufficiency of the lower extremities].

Aim: The objective of the present study was the evaluation of the effectiveness of the combined treatment of the patients presenting with trophic ulcers associated with chronic venous insufficiency of the lower extremities of venous etiology with the application of low-intensity laser therapy (LILT) at different wavelengths.

Material And Methods: The study included the patients presenting with chronic venous insufficiency (CVI) (class C6 in accordance with the CEAP clinical classification). The ultrasonic Doppler examination (USDG) of the lower extremities revealed valvular insufficiency in the saphenous veins in 98.

[The treatment of the patients suffering from acute bacterial external otitis with the use of intravenous blood illumination by low-intensity laser radiation at a wavelength of 445 nm].

Background: The prevalence of allergic reactions to the pharmaceutical products and the development of antibiotic resistance limit the provision of the high-quality medical care to the patients presenting with acute bacterial external otitis media (ABEO).

Aim: The objective of the present study was to evaluate the effectiveness of the treatment of the patients suffering from ABEO with the application of the new technique based on intravenous blood illumination by low-intensity laser radiation at a wavelength of 445 nm (ILBI-445).

Material And Methods: This open comparative clinical study was carried out from April 2017 till June 2017 and included the patients with ABEO who were divided into two groups.

Effectiveness of low level laser therapy for treating male infertility.

In half of the cases, the infertility of the couple is due to the disorder of the male fertility. The leading factors that cause male infertility are urogenital infections, disorders of the immune system, testicular and prostate pathology, as well as endocrine disorders. Low level laser therapy (LLLT) is a very effective physical therapy method, used in many areas of medicine, including obstetrics and gynaecology, andrology and urology; and it is recommended as an integral part of the complex treatment of infertility.

[The commonest therapeutic methods for laser irradiation of blood].

One of the most widely employed methods of laser therapy is laser irradiation of blood (LIB). There are two modifications of this technique, one being intravenous low-intensity laser irradiation of blood (ILIB), the other non-invasive blood irradiation(NLIB). The two methods have been developing independently since either has its advantages and disadvantages.

[Laser therapy for mens infertility. Part 2. Systematic review of clinical trials].

Male infertility is a multifactorial syndrome associated with a wide range of pathological conditions affecting both the sexual and other body systems: endocrine, nervous, blood, and immune. Laser therapy is a form of modern physiotherapy that applies low-intensity laser irradiation (LILI) in various parts of the body. It is widely used in all areas of modern medicine due to its high efficiency, ease of use, the absence of contraindications and side effects.

[Laser therapy for male infertility. Part 1. Etiology and pathogenesis. experimental studies].

Male infertility is associated with a wide range of pathological conditions affecting both the sexual and other body systems: endocrine, nervous, blood, and immune. Laser therapy is a form of modern physiotherapy that applies low-intensity laser radiation in various parts of the body. It is widely used in all areas of modern medicine due to its high efficiency, ease of use, the absence of contraindications and side effects.

Only lasers can be used for low level laser therapy.

The question of lasers' exclusivity, as well as the degree of influence of special properties of low-intensity laser illumination (LILI), such as coherence, polarity and monochromaticity, on the effectiveness of low level laser therapy (LLLT) continues to cause arguments. The study analyzes publications from 1973 to 2016, in which laser and conventional light sources are compared, and the following conclusions are drawn. First, there are a lot of publications with incorrect comparison or unfounded statements.

Efficiency of a New Combined Laser Therapy in Patients With Trophic Ulcers of Lower Extremities and Chronic Venous Insufficiency.

Treating patients with trophic ulcers (TUs) of venous etiology (VE) is a complicated socio-medical and economic problem. One of the ways to increase treatment efficiency can be a complex therapy, including combined laser action. The objective of this study was a comparative evaluation of the efficiency of traditional treatment methods in patients with chronic venous diseases of C6 class, and combined laser therapy (LT) according to a new method by LASMIK® device.

Low-Level Laser Therapy in Russia: History, Science and Practice.

In Russia (formerly USSR) study of biomodulation action (BMA) mechanisms of low-intensity laser irradiation (LILI) began in 1964, immediately after the development of lasers. During the period from 1965 to 1972 several dozens of scientific conferences were held, hundreds of studies were published. Generally, secondary mechanisms and results of LILI effect on patients with various diseases were studied.