Prenatal Exposure to Tobacco and Cannabis in Six Race/Ethnicity Groups during the First Three Years after Legalization of Cannabis for Recreational Use in California.

There are known health concerns linked to prenatal tobacco and cannabis exposures. This study aims to objectively determine the level of exposure to tobacco and cannabis in pregnant individuals from six race/ethnicity groups (Black, Hispanic, Asian Indian, Native American, Vietnamese, and White) in the first three years following legalization of recreational marijuana use in 2018 in California. We used a cross-sectional sample of prenatal screening program participants (2018-2020) from southern and central California (N = 925).

Memristive Effect in Ti C T (MXene) Polyelectrolyte Multilayers.

The emerging novel class of two-dimensional materials - MХenes - have attracted significant research attention. However, there are only few reports on using the most prominent member of the MXene family, Ti C T , as an active material for memristive devices within a polyelectrolyte matrix and its deposition on inert electrodes like ITO and Pt. In this study, we systematically investigate Ti C T MXenes synthesized with two classical delamination agents, such as lithium chloride and tetramethylammonium hydroxide, to identify the most suitable candidate for memristive device applications.

Melamine Barbiturate as a Light-Induced Nanostructured Supramolecular Material for a Bioinspired Oxygen and Organic Radical Trap and Stabilization.

Use of coantioxidant systems is a prospective way to increase the effectiveness of antioxidant species in tissue repair and regeneration. In this paper, we introduce a novel scheme of a reactive oxygen species (ROS) trap and neutralization during self-assembly of supramolecular melamine barbiturate material. The performed reaction chain mimics the biological process of ROS generation in key stages and enables one to obtain stable hydroperoxyl and organic radicals in a melamine barbiturate structure.

Functionalization of chitosan with poly aromatic hydroxyl molecules for improving its antibacterial and antioxidant properties: Practical and theoretical studies.

In this study, the chitosan backbone was functionalized with 2,2',4,4'-tetrahydroxybenzophenone by Schiff base, bonding the molecules into the repeating amine groups. The use of H NMR, FT-IR, and UV-Vis analyses provided compelling evidence of the structure of the newly developed derivatives. The deacetylation degree was calculated to be 75.

Erratum: "Inference of the Local Interstellar Spectra of Cosmic-Ray Nuclei ⩽ 28 with the GALPROP-HELMOD Framework" (2020, ApJS, 250, 27).

[This corrects the article PMC8549769.].

Inference of the Local Interstellar Spectra of Cosmic-Ray Nuclei ⩽ 28 with the GalProp-HelMod Framework.

Composition and spectra of Galactic cosmic rays (CRs) are vital for studies of high-energy processes in a variety of environments and on different scales, for interpretation of -ray and microwave observations, for disentangling possible signatures of new phenomena, and for understanding of our local Galactic neighborhood. Since its launch, AMS-02 has delivered outstanding-quality measurements of the spectra of , , and nuclei: H-O, Ne, Mg, Si. These measurements resulted in a number of breakthroughs; however, spectra of heavier nuclei and especially low-abundance nuclei are not expected until later in the mission.

Dark matter interpretation of the -LAT observations toward the outer halo of M31.

An excess -ray signal toward the outer halo of M31 has recently been reported. Although other explanations are plausible, the possibility that it arises from dark matter (DM) is valid. In this work we interpret the excess in the framework of DM annihilation, using as our representative case WIMP DM annihilating to bottom quarks, and we perform a detailed study of the systematic uncertainty in the -factor for the M31 field.

Cosmic-ray antinuclei as messengers of new physics: status and outlook for the new decade.

The precise measurement of cosmic-ray antinuclei serves as an important means for identifying the nature of dark matter and other new astrophysical phenomena, and could be used with other cosmic-ray species to understand cosmic-ray production and propagation in the Galaxy. For instance, low-energy antideuterons would provide a "smoking gun" signature of dark matter annihilation or decay, essentially free of astrophysical background. Studies in recent years have emphasized that models for cosmic-ray antideuterons must be considered together with the abundant cosmic antiprotons and any potential observation of antihelium.

Deciphering the Local Interstellar Spectra of Secondary Nuclei with the Galprop/Helmod Framework and a Hint for Primary Lithium in Cosmic Rays.

Local interstellar spectra (LIS) of secondary cosmic-ray (CR) nuclei, lithium, beryllium, boron, and partially secondary nitrogen, are derived in the rigidity range from 10 MV to ~200 TV using the most recent experimental results combined with state-of-the-art models for CR propagation in the Galaxy and in the heliosphere. The lithium spectrum appears somewhat flatter at high energies compared to other secondary species, which may imply a primary lithium component. Two propagation packages, GALPROP and HelMod, are combined to provide a single framework that is run to reproduce direct measurements of CR species at different modulation levels, and at both polarities of the solar magnetic field.

Deciphering Residual Emissions: Time-dependent Models for the Nonthermal Interstellar Radiation from the Milky Way.

Cosmic rays (CRs) in the Galaxy are an important dynamical component of the interstellar medium (ISM) that interact with the other major components (interstellar gas and magnetic and radiation fields) to produce broadband interstellar emissions that span the electromagnetic spectrum. The standard modeling of CR propagation and production of the associated emissions is based on a steady-state assumption, where the CR source spatial density is described using a smoothly varying function of position that does not evolve with time. While this is a convenient approximation, reality is otherwise, where primary CRs are produced in and about highly localized regions, e.

AAfrag: Interpolation routines for Monte Carlo results on secondary production in proton-proton, proton-nucleus and nucleus-nucleus interactions.

We provide a compilation of predictions of the QGSJET-II-04m model for the production of secondary species (photons, neutrinos, electrons, positrons, and antinucleons) that are covering a wide range of energies of the beam particles in proton-proton, proton-nucleus, nucleus-proton, and nucleus-nucleus reactions. The current version of QGSJET-II-04m has an improved treatment of the production of secondary particles at low energies: the parameters of the hadronization procedure have been fine-tuned, based on a number of recent benchmark experimental data, notably, from the LHCf, LHCb, and NA61 experiments. Our results for the production spectra are made publicly accessible through the interpolation routines AAfrag which are described below.

AMS-100: The Next Generation Magnetic Spectrometer in Space - An International Science Platform for Physics and Astrophysics at Lagrange Point 2.

The next generation magnetic spectrometer in space, AMS-100, is designed to have a geometrical acceptance of 100 m sr and to be operated for at least ten years at the Sun-Earth Lagrange Point 2. Compared to existing experiments, it will improve the sensitivity for the observation of new phenomena in cosmic rays, and in particular in cosmic antimatter, by at least a factor of 1000. The magnet design is based on high temperature superconductor tapes, which allow the construction of a thin solenoid with a homogeneous magnetic field of 1 Tesla inside.

-LAT Observations of -Ray Emission toward the Outer Halo of M31.

The Andromeda galaxy is the closest spiral galaxy to us and has been the subject of numerous studies. It harbors a massive dark matter halo, which may span up to ~600 kpc across and comprises ~90% of the galaxy's total mass. This halo size translates into a large diameter of 42° on the sky, for an M31-Milky Way (MW) distance of 785 kpc, but its presumably low surface brightness makes it challenging to detect with -ray telescopes.

Cosmic-Ray Propagation in Light of the Recent Observation of Geminga.

The High Altitude Water Cherenkov (HAWC) telescope recently observed extended emission around the Geminga and PSR B0656+14 pulsar wind nebulae (PWNe). These observations have been used to estimate cosmic-ray (CR) diffusion coefficients near the PWNe that appear to be more than two orders of magnitude smaller than the diffusion coefficients typically derived for the interstellar medium from measured abundances of secondary species in CRs. Two-zone diffusion models have been proposed as a solution to this discrepancy, where the slower diffusion zone (SDZ) is confined to a small region around the PWN.

Unresolved Gamma-Ray Sky through its Angular Power Spectrum.

The gamma-ray sky has been observed with unprecedented accuracy in the last decade by the Fermi -large area telescope (LAT), allowing us to resolve and understand the high-energy Universe. The nature of the remaining unresolved emission [unresolved gamma-ray background (UGRB)] below the LAT source detection threshold can be uncovered by characterizing the amplitude and angular scale of the UGRB fluctuation field. This Letter presents a measurement of the UGRB autocorrelation angular power spectrum based on eight years of Fermi-LAT Pass 8 data products.

Current status and desired precision of the isotopic production cross sections relevant to astrophysics of cosmic rays: Li, Be, B, C, and N.

The precision of the current generation of cosmic-ray (CR) experiments, such as AMS-02, PAMELA, CALET, and ISS-CREAM, is now reaching ≈1-3% in a wide range in energy per nucleon from GeV/nucleon to multi-TeV/nucleon. Their correct interpretation could potentially lead to discoveries of new physics and subtle effects that were unthinkable just a decade ago. However, a major obstacle in doing so is the current uncertainty in the isotopic production cross sections that can be as high as 20-50% or even larger in some cases.

Galactic PeVatrons and helping to find them: Effects of galactic absorption on the observed spectra of very high energy -ray sources.

Identification of the cosmic-ray (CR) "PeVatrons," which are sources capable of accelerating particles to ~10 eV energies and higher, may lead to resolving the long-standing question of the origin of the spectral feature in the all-particle CR spectrum known as the "knee." Because CRs with these energies are deflected by interstellar magnetic fields identification of individual sources and determination of their spectral characteristics is more likely via very high energy -ray emissions, which provide the necessary directional information. However, pair production on the interstellar radiation field (ISRF) and cosmic microwave background (CMB) leads to steepening of the high energy tails of -ray spectra, and should be corrected for to enable true properties of the spectrum at the source to be recovered.

Deciphering the Local Interstellar Spectra of Primary Cosmic-Ray Species with helmod.

Local interstellar spectra (LIS) of primary cosmic ray (CR) nuclei, such as helium, oxygen, and mostly primary carbon are derived for the rigidity range from 10 MV to ~200 TV using the most recent experimental results combined with the state-of-the-art models for CR propagation in the Galaxy and in the heliosphere. Two propagation packages, GALPROP and helmod, are combined into a single framework that is used to reproduce direct measurements of CR species at different modulation levels, and at both polarities of the solar magnetic field. The developed iterative maximum-likelihood method uses GALPROP-predicted LIS as input to helmod, which provides the modulated spectra for specific time periods of the selected experiments for model-data comparison.

GALPROP cosmic-ray propagation code: recent results and updates.

Information on cosmic-ray (CR) composition comes from direct CR measurements while their distribution in the Galaxy is evaluated from observations of their associated diffuse emission in the range from radio to gamma rays. Even though the main interaction processes are identified, more and more precise observations provide an opportunity to study more subtle effects and pose a challenge to the propagation models. GALPROP is a sophisticated CR propagation code that is being developed for about 20 years.

The Three-dimensional Spatial Distribution of Interstellar Gas in the Milky Way: Implications for Cosmic Rays and High-energy Gamma-ray Emissions.

Direct measurements of cosmic ray (CR) species combined with observations of their associated γ-ray emissions can be used to constrain models of CR propagation, trace the structure of the Galaxy, and search for signatures of new physics. The spatial density distribution of interstellar gas is a vital element for all these studies. So far, models have employed the 2D cylindrically symmetric geometry, but their accuracy is well behind that of the available data.

Einstein@Home discovers a radio-quiet gamma-ray millisecond pulsar.

Millisecond pulsars (MSPs) are old neutron stars that spin hundreds of times per second and appear to pulsate as their emission beams cross our line of sight. To date, radio pulsations have been detected from all rotation-powered MSPs. In an attempt to discover radio-quiet gamma-ray MSPs, we used the aggregated power from the computers of tens of thousands of volunteers participating in the Einstein@Home distributed computing project to search for pulsations from unidentified gamma-ray sources in Fermi Large Area Telescope data.

HelMod in the Works: From Direct Observations to the Local Interstellar Spectrum of Cosmic-Ray Electrons.

The local interstellar spectrum (LIS) of cosmic-ray (CR) electrons for the energy range 1 MeV to 1 TeV is derived using the most recent experimental results combined with the state-of-the-art models for CR propagation in the Galaxy and in the heliosphere. Two propagation packages, GALPROP and HelMod, are combined to provide a single framework that is run to reproduce direct measurements of CR species at different modulation levels, and at both polarities of the solar magnetic field. An iterative maximum-likelihood method is developed that uses GALPROP-predicted LIS as input to HelMod, which provides the modulated spectra for specific time periods of the selected experiments for model-data comparison.