[A method for studying intravascular platelet aggregation in vitro].

A simple available method for evaluating intravascular platelet aggregation is proposed. It consists in graphic recording of disaggregation of platelet-rich citrate plasma, which indicates the degree of intravascular aggregation. Intravascular aggregation is notably increased in coronary patients and negligible in normal subjects.

[Burden of hereditary diseases in residents of the Mari El Republic].

A summary of the medical genetic studies of the Marii El population is presented. A total of 276,900 people, 110,894 and 166,006 urban and rural inhabitants, respectively, were examined. Regarding the ethnic composition, the studied population was mostly Mari (61.

[Diversity of hereditary pathology in the population of Marii El Republic and its differentiation with respect to gene frequencies for hereditary diseases].

The diversity of Mendelian hereditary pathology was studied in Marii El Republic. In total, 276,900 subjects, including 171,151 Maris and 88,714 Russians, living in seven raions (districts) were studied. Fifty-five autosomal dominant disease entities were found, with more than ten diseases having a frequency of 1:50,000 people or higher.

[Meadow maris: a genetic landscape].

The distribution of the most frequent family names was analyzed in five regions of the Marii El republic, and diagrams of their genetic landscape were constructed. Based on the diagrams, conclusions were drawn regarding the genetic subdivision of the corresponding populations and the boundary between elementary populations within them.

[Medico-genetic study of residents of Marii El republic: burden of hereditary diseases in four regions of the republic].

A medical genetic study of Orshanskii, Morkinskii, Sovetskii, and Semurskii raions (districts) of the Marii El Republic was performed. The total number of subjects examined was 115,743. Meadow Maris and Russians accounted for the most part of the populations of the districts studied.

[The marital-migrational structure of the rural and urban populations of the Marii El republic].

The marital-migrational structure of five districts of the Marii El Republic was studied on the basis of marital records. The average values of ethnic marriage assortativeness were 1.18, 1.

[Meadow Maris: genes, surnames and migrations].

The matrices of genetic distances, calculated from the frequencies of surnames and the ABO, TF, GC, PI, HP, ACP1, and PGM1 genes, were compared with one another and with the migration matrix. The correlation coefficient between the "gene" and "surname" matrices was 0.71 +/- 0.

[The meadow Mari: inbreeding and endogamy].

The genetic structure of Lugovye Maris was studied on the basis of marital migration. Malecot's parameters of isolation and endogamy index were estimated in four rations of the Marii El Republic, which is populated by Maris. High values of the endogamy index (0.

[Monogenic hereditary diseases in Gorno-Mariĭskiĭ district of Mariĭ El republic].

The population of Gornomariiskii raion, Marii El Republic, primarily made up of mountain Marii, was subjected to medical genetic examination. The size of the entire population is 54853. Estimates of hereditary pathology in urban and rural populations of the raion were obtained.

[Genetic-demographic characteristics of highland Mari].

Genetic and demographic characteristics of the population of the Gornomariiskii raion, Marii El Republic, were estimated. The length of generation was 28.16 +/- 0.

[Population sturcture of the Gorno-Mariĭskiĭ region of the Mariĭ El Republic].

The genetic structure of the population of the Gorno-Mariiskii raion, Marii El Republic, was studied. The population consists of two major groups, highland Mari and Russians. The former constitute the majority of the rural population, and the latter, the majority of the urban one.