Publications by authors named "Moshe Snir"
Article Synopsis
- The study aimed to compare how ocular motility deviation in strabismus patients changed using cycloplegic eye drops versus a prism adaptation test.
- Data was collected from 43 patients who had strabismus surgery, focusing on 33 with exotropia, measuring motility deviation at various times during the tests.
- Results showed that prism adaptation was statistically more effective than cycloplegic drops at assessing motility both during the tests and shortly after, making it the preferred method for pre-surgical evaluation.
Purpose: Persistent fetal vasculature (PFV) is a unique ocular disorder usually presenting early in life. The unregressed embryonal hyaloid vasculature poses a risk of severe ocular complications leading to decreased visual acuity. Surgery is the mainstay of therapy in complicated cases.
View Article and Find Full Text PDFPurpose: To model and analyse the ocular biometry of new-born infants.
Methods: This work is based on previously published data of a cohort of 66 new-born infants aged 0-3 days. After exclusion of seven myopic subjects, the available retinoscopy, keratometry and ultrasound biometry data were analysed, along with calculated parameters such as lens power and whole eye power.
Article Synopsis
- The study investigates the incidence of horizontal misalignment that requires surgery in children with congenital Brown syndrome, based on medical records from a specific medical center over 18 years.
- Among the 16 patients studied, most (88%) underwent surgery to correct compensatory head positions, with a notable portion also having primary position horizontal deviations.
- Post-surgery results showed a significant reduction in horizontal deviation, highlighting the need for addressing this issue during surgical intervention for congenital Brown syndrome.
Article Synopsis
- This study explores unique pediatric neurological cases to better understand the challenges in distinguishing between posterior reversible encephalopathy syndrome (PRES), hypoxic-ischemic insult (HII), and acute toxic leukoencephalopathy (ATL).
- Three children were treated for conditions suggesting PRES, HII, or ATL, each presenting with blindness after various strenuous medical episodes.
- The findings indicate that diagnosing and managing these conditions requires a careful review of their clinical and imaging characteristics, and the study calls for further research into the causes and implications of PRES.
Medical And Surgical Management Of Orbital Cellulitis In Children.
Folia Med (Plovdiv)
December 2015
Objective: The purpose of this study was to identify features of orbital cellulitis that predict response to conservative treatment without surgical intervention and factors associated with a decision for surgery.
Patients And Methods: The medical files of patients diagnosed with orbital cellulitis at a tertiary medical center in central Israel between 1995 and 2010 were reviewed for clinical data, diagnosis, complications, and type of treatment. Comparison was made between patients treated with antibiotics and patients treated with antibiotics and surgery.
Article Synopsis
- Retinopathy of prematurity (ROP) is a condition in premature babies that can cause severe vision loss due to abnormal eye blood vessel development.
- A study used B-scan ocular ultrasonography to assess the superior ophthalmic vein (SOV) in premature infants, comparing those diagnosed with ROP to those without it.
- The findings revealed that 95.4% of eyes with ROP showed dilation of the SOV, whereas only 15.6% of eyes without ROP exhibited this dilation, indicating a potential link between ROP and changes in the SOV.
Article Synopsis
- The study examined how peripapillary optical coherence tomography (OCT) can track optic nerve damage in children with craniopharyngioma, analyzing medical records from 20 pediatric patients treated from 1999 to 2011.
- Key findings included a significant difference in retinal nerve fiber layer (RNFL) thickness between healthy eyes and those with optic neuropathy, with thinner RNFL correlating to poorer visual acuity and visual field loss.
- The researchers concluded that OCT is a valuable tool for assessing optic nerve health in these patients and suggested further studies to explore its effectiveness in monitoring ongoing nerve damage over time.
We report the case of a 12-week-old boy presenting with increased cholesterol and triglyceride levels. Examination revealed lipemia retinalis. Genetic evaluation demonstrated lipoprotein lipase deficiency.
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- The study aimed to see if the time it takes to normalize increased intracranial pressure (ICP) due to intraventricular hemorrhage (IVH) affects treatment for retinopathy of prematurity (ROP) in premature infants.
- Researchers reviewed medical records of premature infants (≤ 35 weeks gestation or ≤ 1500g birth weight) who had both ROP and IVH, comparing those treated for only ICP versus those treated for both conditions.
- Results showed that infants treated for both ROP and ICP took longer to normalize ICP (100 days) compared to those treated for ICP alone (45 days), suggesting that quicker management of ICP might lessen the need for ROP treatment.
The aim of the study was to determine if early steroid treatment of infantile spasms is associated with ocular complications years after its termination. Twenty-five patients with infantile spasms who underwent prolonged treatment with intramuscular synthetic adrenocorticotropic hormone (ACTH) and oral prednisone were evaluated for ocular complications 2 to 33 years after treatment cessation. Patients were followed by an ophthalmic examination that included anterior and posterior segments and measurement of intraocular pressure.
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- This study analyzed severe, irreversible visual loss in children with brain tumors caused by optic neuropathy, focusing on 10 patients who fell within specific criteria after reviewing data from a pediatric neuro-ophthalmology center.
- Among the children, initial visual assessments revealed varying degrees of blindness, with common factors like direct optic nerve compression and increased intracranial pressure contributing to their conditions, particularly post-surgery.
- The findings highlight that even successful tumor removal can lead to significant vision loss, particularly in 40% of cases where deterioration was noted during the perioperative period, necessitating awareness among clinicians regarding these risks.
Article Synopsis
- The study examines the effectiveness of intravitreal bevacizumab as either a main or additional treatment for severe retinopathy of prematurity in infants.
- Nine infants with severe cases were analyzed; they had varying levels of gestational age and birth weight, and required treatment due to progression despite laser therapies.
- Results showed that bevacizumab successfully reduced active blood vessel growth in all treated eyes, with favorable anatomical outcomes and no significant complications reported.
Article Synopsis
- The study aimed to assess how effective a sub-Tenon's block with ropivacaine is in reducing post-operative pain after strabismus surgery, a procedure that can cause significant discomfort.
- Conducted on 79 patients aged 1 to 65, half received the anesthetic at the end of surgery, and pain levels were measured using a visual analog scale at various times after the procedure.
- Results showed that patients who received the ropivacaine block experienced significantly less pain 12-16 hours post-surgery, required fewer additional painkillers, and reported higher satisfaction compared to those who did not receive the block.
Article Synopsis
- - The study aimed to assess how stable intraocular pressure (IOP) measurements are when taken successively in patients with glaucoma.
- - Sixty-seven glaucoma patients underwent four IOP measurements, showing a significant decrease in pressure with each successive reading, unlike the control group of cataract surgery patients, who showed no notable changes.
- - The findings suggest that IOP in glaucoma patients tends to decrease with repeated measurements, whereas those without glaucoma maintain stable pressure levels.
Article Synopsis
- The study aimed to identify when the oculocephalic reflex is suppressed in infants and how it relates to clinical factors like age and weight.
- Conducted on 325 healthy babies, the reflex was tested by moving their heads and observing eye movements, determining that 75% had the reflex suppressed by 11.5 weeks.
- Results indicated that postpartum age was the most significant factor influencing the suppression, and the reflex’s disappearance is a normal part of visual system maturation.*
Long-term ophthalmological follow-up of children with Parinaud syndrome.
Ophthalmic Surg Lasers Imaging
July 2011
Article Synopsis
- The study evaluates the long-term eye health outcomes of six children diagnosed with tumor-related Parinaud syndrome between 2000 and 2007, all experiencing symptoms of increased intracranial pressure.
- The children received treatments including surgical shunting, complete or partial tumor resection, and additional therapies like chemotherapy and radiation, with most showing stable or improved vision after treatment.
- Follow-up after an average of 4.2 years revealed some persistent eye issues in most patients, highlighting that children may have lasting, though subtle, eye problems even after successful treatment of Parinaud syndrome.
Article Synopsis
- The study investigated how intravitreal injection of bevacizumab (Avastin) affects the growth and structure of young rabbits' eyes.
- Twelve rabbits received the treatment in one eye, while six additional rabbits acted as control subjects without any injection.
- Results showed no significant differences in eye growth or structure between treated and untreated eyes, suggesting that bevacizumab does not negatively impact the development of young rabbit eyes.
Ocular complications in children and adolescents following renal transplantation.
Pediatr Transplant
February 2010
Ocular complications after renal transplantation are common in adults. Nevertheless, data regarding these complications in children are insufficient. The purpose of the present study was to assess ocular morbidity in pediatric renal graft recipients.
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- * In a review of 28 patients (average age 13.4), half had previously undergone surgery, with an overall success rate of 60.7%, which showed no significant difference based on the type of strabismus (esotropia vs. exotropia) or prior treatment.
- * The findings suggest that the effectiveness of combined surgery is consistent regardless of the specific type of horizontal deviation or previous surgical history.
Purpose: To evaluate the efficacy of topical lomefloxacin 0.3% versus chloramphenicol 0.2% with polymyxin B 2500 U/ml in the treatment of patients after strabismus surgery.
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- The study evaluates the effectiveness of infrared diode laser photocoagulation (DLPC) for treating threshold retinopathy of prematurity (ROP) in premature neonates.
- It involved reviewing charts of 100 neonates treated at a tertiary center, revealing that 92.3% had favorable anatomical outcomes and a significant portion had refractive issues like myopia.
- The findings suggest that DLPC is a safe and effective treatment, particularly for neonates with lower birth weight and gestational age, who need more intensive laser interventions.
Article Synopsis
- The study aimed to examine the impact of in vitro fertilization (IVF) on the eye development of full-term infants.
- It involved a case-control approach, comparing 32 IVF-conceived infants with 34 naturally conceived infants, measuring various health metrics and conducting a comprehensive eye exam.
- Results showed no significant differences in most eye development metrics, suggesting IVF does not negatively affect early eye development in healthy infants, although smaller IVF infants exhibited some variations in corneal characteristics that might indicate delayed maturation.
Article Synopsis
- The study compares the effectiveness of augmented superior oblique Z-tenotomy (SOZT) to standard SOZT in treating superior oblique overaction and Brown's syndrome in patients with A or V pattern anisotropia.
- Sixteen patients underwent augmented SOZT, while 20 historical controls received standard SOZT, revealing significant improvements in reducing overaction and alignment issues for those in the augmented group.
- Augmented SOZT showed higher success rates, with no need for reoperations in the augmented group, while 37.5% of controls needed reoperation; it also allows for intraoperative adjustments for better outcomes.
Article Synopsis
- The study aimed to compare the incidence and severity of retinopathy of prematurity (ROP) in infants conceived naturally versus those conceived through assisted reproductive technologies (ART), as well as examining the effects of singleton versus multiple births on ROP.
- Data was collected from 363 infants born in a specific neonatal unit between 1998 and 2000, noting factors like gestational age, birth weight, and type of conception, with ophthalmological exams conducted routinely.
- Results showed no significant differences in ROP occurrence or severity between the two conception methods, but singletons had a higher rate of advanced ROP compared to twins and triplets.