Publications by authors named "Moshe Lusky"

Purpose: To compare changes in anterior segment parameters following ExPRESS Mini Glaucoma Shunt surgery vs. trabeculectomy using the Pentacam rotating Scheimpflug camera.

Methods: In this prospective, comparative study, 27 patients with glaucoma treated at the Rabin Medical Center from 2009 to 2013 were enrolled in this prospective comparative study: 19 participants (19 eyes) underwent ExPRESS shunt implantation and 12 (13 eyes) underwent trabeculectomy.

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Article Synopsis
  • The study aimed to investigate the early effects of cyclosporine on the optic nerve for the first time, involving 192 eyes from 98 patients.
  • Results showed that older age (over 46 years) was significantly linked to optic neuropathy in patients taking cyclosporine, while a longer treatment duration had a non-significant correlation.
  • The authors recommend including optic nerve function tests, like visual evoked potential (VEP), in the follow-up care for patients on cyclosporine to monitor potential issues.
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Purpose: The aim of this study was to evaluate the effect of Ex-PRESS Miniature Glaucoma Implant surgery on corneal curvature and anterior segment parameters obtained with the Pentacam rotating Scheimpflug camera (Oculus Inc.).

Patients/methods: In this prospective study, a total of 19 eyes of 19 consecutive patients (11 men, 8 women) were evaluated preoperatively, on the first postoperative day, and at 1 week, 1 month, and 3 months postoperatively with the Pentacam.

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Purpose: One of the leading methods for optic nerve head assessment in glaucoma remains stereoscopic photography. This study compared conventional film and digital stereoscopy in the quantitative and qualitative assessment of the optic nerve head in glaucoma and glaucoma suspect patients.

Methods: Fifty patients with glaucoma or suspected glaucoma underwent stereoscopic photography of the optic nerve head with a 35-mm color slide film and a digital camera.

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Article Synopsis
  • - The study aimed to assess how stable intraocular pressure (IOP) measurements are when taken successively in patients with glaucoma.
  • - Sixty-seven glaucoma patients underwent four IOP measurements, showing a significant decrease in pressure with each successive reading, unlike the control group of cataract surgery patients, who showed no notable changes.
  • - The findings suggest that IOP in glaucoma patients tends to decrease with repeated measurements, whereas those without glaucoma maintain stable pressure levels.
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Purpose: To search for the genetic cause of juvenile open-angle glaucoma (JOAG) in a Caucasian family and to perform genotype/phenotype correlation studies in the kindred.

Methods: Six members of a three-generation family originating from Uzbekistan and now living in the Middle East were recruited from one large clinic in Israel. Ophthalmologic investigations comprised of visual field assessments, intraocular pressure measurements, optic disc evaluation, and gonioscopy.

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Purpose: The indications for enucleation and evisceration have decreased in the last decade, most probably because of improved treatment modalities. The aim of the study was to evaluate the use of these procedures in the last 26 years in our medical centre.

Methods: This study included all patients who underwent enucleation or evisceration at Rabin Medical Center from 1981 to 2007.

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Purpose: To test the hypothesis that puberty is a risk factor for poorer visual outcome in idiopathic intracranial hypertension (IIH).

Design: Retrospective chart review case series.

Setting: Tertiary referral center, neuro-ophthalmology unit.

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Purpose: To describe the outcome of the use of fibrin adhesive (Quixil) in penetrating trabeculectomy in a rabbit model.

Methods: Fibrin adhesive was used experimentally to attach the conjunctiva and the scleral flap in two groups of 17 New Zealand albino adult rabbits (34 eyes). In the first experiment (20 eyes), the fibrin adhesive was used to reattach the tissue after conjunctival peritomy and scleral flap only in 14 eyes (experiment I).

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Background And Objective: To compare the use of cyclocryotherapy and diode laser cyclophotocoagulation for the treatment of uncontrolled intraocular pressure.

Patients And Methods: Seventy consecutive patients (70 eyes) treated for high, unresponsive intraocular pressure during a 4-year period with cyclocryotherapy (n = 38) or diode laser cyclophotocoagulation (n = 32) with a follow-up period of at least 3 months (mean follow-up = 15.7 months) were compared for intraocular pressure, visual acuity, and complication rate.

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Purpose: The purpose of this study is to demonstrate feasibility of using our novel concept, termed competitive quenching, for protecting the choroidal extravascular compartment and retinal pigment epithelium (RPE) from verteporfin (VP)-induced phototoxicity using hypericin. Furthermore, we aim to achieve partitioning of the quencher, hypericin, in the extravascular space and VP within the microvascular compartment of the chorio-retinal complex in vivo.

Methods: We protect RPE cells from damage inflicted by photoactivated VP by introducing hypericin into these cells prior to photosensitization to quench the photosensitizing activity of VP.

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Objective: To determine the levels of plasminogen activator inhibitor-1 (PAI-1) and total protein in the aqueous humor of patients with glaucoma vs those without glaucoma.

Methods: A total of 125 aqueous humor samples (50-150 microL each) were collected at 3 institutions from patients with glaucoma and a control group of patients with cataract. Fifteen samples were excluded, and the levels of PAI-1 antigen were determined by enzyme-linked immunosorbent assay in 110 samples (36 glaucoma and 74 control).

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Objective: To examine the reliability of Swedish Interactive Thresholding Algorithm Fast (SITA Fast) visual fields (VFs) in prepubertal idiopathic intracranial hypertension (IIH) and to compare whether age, gender, or severity of visual outcome influenced the reliability of VF tests.

Design: Prospective, longitudinal cohort study.

Participants: Twenty-six prepubertal children (<11 years of age; mean age, 7.

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Purpose: To evaluate the ocular changes and medical and surgical therapy after high-dose systemic steroid treatment in babies with infantile spasm and hypsarrhythmia.

Design: Retrospective, noncomparative, interventional case series.

Participants: In 5 of the 9 (55%) babies with infantile spasm exposed to systemic corticosteroid treatment, an increase in intraocular pressure (IOP) and optic disc cupping was observed.

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